Harriet de Wit

Research interests

Publications

• Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

  Nature Genetics · 2019 · 10.1038/s41588-018-0309-3

• GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability

  Nature Neuroscience · 2018 · https://doi.org/10.1038/s41593-018-0206-1

• The latent structure of impulsivity: impulsive choice, impulsive action, and impulsive personality traits

  Psychopharmacology · 2016 · https://doi.org/10.1007/s00213-016-4372-0

• Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

  JAMA Psychiatry · 2015 · https://doi.org/10.1001/jamapsychiatry.2015.0554

• Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium

  Behavior Genetics · 2015 · https://doi.org/10.1007/s10519-015-9735-5

• Rewarding, Stimulant, and Sedative Alcohol Responses and Relationship to Future Binge Drinking

  Archives of General Psychiatry · 2011 · https://doi.org/10.1001/archgenpsychiatry.2011.26

• Behavioral and Biological Indicators of Impulsivity in the Development of Alcohol Use, Problems, and Disorders

  Alcoholism Clinical and Experimental Research · 2010 · 10.1111/j.1530-0277.2010.01217.x

• Genetics of caffeine consumption and responses to caffeine

  Psychopharmacology · 2010 · 10.1007/s00213-010-1900-1

• Impulsivity as a determinant and consequence of drug use: a review of underlying processes

  Addiction Biology · 2008 · https://doi.org/10.1111/j.1369-1600.2008.00129.x

• Preference for Immediate over Delayed Rewards Is Associated with Magnitude of Ventral Striatal Activity

  Journal of Neuroscience · 2006 · https://doi.org/10.1523/jneurosci.3446-06.2006

• IQ and nonplanning impulsivity are independently associated with delay discounting in middle-aged adults

  Personality and Individual Differences · 2006 · 10.1016/j.paid.2006.06.026

• Dimensions of impulsive behavior: Personality and behavioral measures

  Personality and Individual Differences · 2005 · https://doi.org/10.1016/j.paid.2005.03.024

• Effects of THC on Behavioral Measures of Impulsivity in Humans

  Neuropsychopharmacology · 2003 · 10.1038/sj.npp.1300176

• Association Between A2a Receptor Gene Polymorphisms and Caffeine-Induced Anxiety

  Neuropsychopharmacology · 2003 · 10.1038/sj.npp.1300232

• Acute Administration of d-Amphetamine Decreases Impulsivity in Healthy Volunteers

  Neuropsychopharmacology · 2002 · https://doi.org/10.1016/s0893-133x(02)00343-3

• The reinstatement model of drug relapse: history, methodology and major findings

  Psychopharmacology · 2002 · https://doi.org/10.1007/s00213-002-1224-x

• Effects of dopaminergic drugs on delayed reward as a measure of impulsive behavior in rats

  Psychopharmacology · 2000 · 10.1007/s002130000402

• Effects of d-Amphetamine and alcohol on a measure of behavioral inhibition in rats.

  Behavioral Neuroscience · 2000 · 10.1037/0735-7044.114.4.838

• DELAY OR PROBABILITY DISCOUNTING IN A MODEL OF IMPULSIVE BEHAVIOR: EFFECT OF ALCOHOL

  Journal of the Experimental Analysis of Behavior · 1999 · https://doi.org/10.1901/jeab.1999.71-121

• DETERMINATION OF DISCOUNT FUNCTIONS IN RATS WITH AN ADJUSTING‐AMOUNT PROCEDURE

  Journal of the Experimental Analysis of Behavior · 1997 · https://doi.org/10.1901/jeab.1997.67-353

• Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants.

  Psychological Review · 1984 · https://doi.org/10.1037//0033-295x.91.2.251

• Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants.

  Psychological Review · 1984 · https://doi.org/10.1037/0033-295x.91.2.251

• Reinstatement of cocaine-reinforced responding in the rat

  Psychopharmacology · 1981 · https://doi.org/10.1007/bf00432175

• Neuroleptic-Induced "Anhedonia" in Rats: Pimozide Blocks Reward Quality of Food

  Science · 1978 · https://doi.org/10.1126/science.566469

• Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine.

  Canadian Journal of Psychology/Revue Canadienne de Psychologie · 1977 · https://doi.org/10.1037/h0081662

• Both Positive Reinforcement and Conditioned Aversion from Amphetamine and from Apomorphine in Rats

  Science · 1976 · 10.1126/science.1257748

Current projects

No projects listed.