Massimo Loda

Research interests

Publications

• MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets

  Nature Communications · 2022 · https://doi.org/10.1038/s41467-022-30257-z

• Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-021-21361-7

• Genomic correlates of clinical outcome in advanced prostate cancer

  Proceedings of the National Academy of Sciences · 2019 · https://doi.org/10.1073/pnas.1902651116

• The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance

  Clinical Cancer Research · 2019 · https://doi.org/10.1158/1078-0432.ccr-19-1423

• Integrative Clinical Genomics of Advanced Prostate Cancer

  Cell · 2015 · https://doi.org/10.1016/j.cell.2015.06.053

• A Phase I/II Study for Analytic Validation of 89Zr-J591 ImmunoPET as a Molecular Imaging Agent for Metastatic Prostate Cancer

  Clinical Cancer Research · 2015 · https://doi.org/10.1158/1078-0432.ccr-15-0552

• Integrative Clinical Genomics of Advanced Prostate Cancer

  Cell · 2015 · https://doi.org/10.1016/j.cell.2015.05.001

• EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent

  Science · 2012 · https://doi.org/10.1126/science.1227604

• SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

  Nature · 2011 · https://doi.org/10.1038/nature09677

• MYC regulation of a “poor-prognosis” metastatic cancer cell state

  Proceedings of the National Academy of Sciences · 2010 · https://doi.org/10.1073/pnas.0914203107

• Fatty Acid Synthase As a Potential Therapeutic Target in Cancer

  Future Oncology · 2010 · https://doi.org/10.2217/fon.10.11

• The landscape of somatic copy-number alteration across human cancers

  Nature · 2010 · https://doi.org/10.1038/nature08822

• Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer

  Cell · 2009 · https://doi.org/10.1016/j.cell.2009.04.056

• High-throughput oncogene mutation profiling in human cancer

  Nature Genetics · 2007 · 10.1038/ng1975

• Sensitive Sequencing Method for KRAS Mutation Detection by Pyrosequencing

  Journal of Molecular Diagnostics · 2005 · https://doi.org/10.1016/s1525-1578(10)60571-5

• Gene expression correlates of clinical prostate cancer behavior

  Cancer Cell · 2002 · https://doi.org/10.1016/s1535-6108(02)00030-2

• Multiclass cancer diagnosis using tumor gene expression signatures

  Proceedings of the National Academy of Sciences · 2001 · https://doi.org/10.1073/pnas.211566398

• Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

  Proceedings of the National Academy of Sciences · 2001 · https://doi.org/10.1073/pnas.191502998

• p63 Is a Prostate Basal Cell Marker and Is Required for Prostate Development

  American Journal Of Pathology · 2000 · https://doi.org/10.1016/s0002-9440(10)64814-6

Current projects

No projects listed.