Jeffrey S. Ross

Research interests

Publications

• Pan-Cancer Analysis of BRCA1 and BRCA2 Genomic Alterations and Their Association With Genomic Instability as Measured by Genome-Wide Loss of Heterozygosity

  JCO Precision Oncology · 2020 · https://doi.org/10.1200/po.19.00345

• Impact of Molecular Subtyping and Immune Infiltration on Pathological Response and Outcome Following Neoadjuvant Pembrolizumab in Muscle-invasive Bladder Cancer

  European Urology · 2020 · https://doi.org/10.1016/j.eururo.2020.02.028

• Real-Time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations That Might Be Targeted With Existing Drugs or Used as Biomarkers

  Gastroenterology · 2019 · https://doi.org/10.1053/j.gastro.2019.02.037

• Updated Results of PURE-01 with Preliminary Activity of Neoadjuvant Pembrolizumab in Patients with Muscle-invasive Bladder Carcinoma with Variant Histologies

  European Urology · 2019 · https://doi.org/10.1016/j.eururo.2019.10.026

• Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-019-0407-5

• Prospective Comprehensive Genomic Profiling of Primary and Metastatic Prostate Tumors

  JCO Precision Oncology · 2019 · https://doi.org/10.1200/po.18.00283

• Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open-Label, Single-Arm, Phase II Study

  Journal of Clinical Oncology · 2018 · https://doi.org/10.1200/jco.18.01148

• STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS -Mutant Lung Adenocarcinoma

  Cancer Discovery · 2018 · https://doi.org/10.1158/2159-8290.cd-18-0099

• Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers

  Clinical Cancer Research · 2018 · https://doi.org/10.1158/1078-0432.ccr-18-0373

• ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer

  JNCI Journal of the National Cancer Institute · 2017 · https://doi.org/10.1093/jnci/djx089

• Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting

  Blood · 2016 · https://doi.org/10.1182/blood-2015-08-664649

• Characterization of 298 Patients with Lung Cancer Harboring MET Exon 14 Skipping Alterations

  Journal of Thoracic Oncology · 2016 · https://doi.org/10.1016/j.jtho.2016.06.004

• FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors

  Journal of Translational Medicine · 2016 · https://doi.org/10.1186/s12967-016-1075-6

• Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease

  Gastroenterology · 2016 · https://doi.org/10.1053/j.gastro.2016.04.001

• Biliary cancer: Utility of next‐generation sequencing for clinical management

  Cancer · 2016 · https://doi.org/10.1002/cncr.30254

• Broad, Hybrid Capture–Based Next-Generation Sequencing Identifies Actionable Genomic Alterations in Lung Adenocarcinomas Otherwise Negative for Such Alterations by Other Genomic Testing Approaches

  Clinical Cancer Research · 2015 · https://doi.org/10.1158/1078-0432.ccr-14-2683

• Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

  Cancer Discovery · 2015 · https://doi.org/10.1158/2159-8290.cd-15-0913

• The distribution of BRAF gene fusions in solid tumors and response to targeted therapy

  International Journal of Cancer · 2015 · https://doi.org/10.1002/ijc.29825

• Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Site

  JAMA Oncology · 2015 · https://doi.org/10.1001/jamaoncol.2014.216

• Phase III Multinational, Randomized, Double-Blind, Placebo-Controlled Study of Tivantinib (ARQ 197) Plus Erlotinib Versus Erlotinib Alone in Previously Treated Patients With Locally Advanced or Metastatic Nonsquamous Non–Small-Cell Lung Cancer

  Journal of Clinical Oncology · 2015 · https://doi.org/10.1200/jco.2014.60.7317

• New Routes to Targeted Therapy of Intrahepatic Cholangiocarcinomas Revealed by Next-Generation Sequencing

  The Oncologist · 2014 · https://doi.org/10.1634/theoncologist.2013-0352

• Emergence of Constitutively Active Estrogen Receptor-α Mutations in Pretreated Advanced Estrogen Receptor–Positive Breast Cancer

  Clinical Cancer Research · 2014 · https://doi.org/10.1158/1078-0432.ccr-13-2332

• Kinase fusions are frequent in Spitz tumours and spitzoid melanomas

  Nature Communications · 2014 · https://doi.org/10.1038/ncomms4116

• Response to Cabozantinib in Patients with RET Fusion-Positive Lung Adenocarcinomas

  Cancer Discovery · 2013 · https://doi.org/10.1158/2159-8290.cd-13-0035

• Molecular Profiling of the Residual Disease of Triple-Negative Breast Cancers after Neoadjuvant Chemotherapy Identifies Actionable Therapeutic Targets

  Cancer Discovery · 2013 · https://doi.org/10.1158/2159-8290.cd-13-0286

• Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

  Nature Biotechnology · 2013 · https://doi.org/10.1038/nbt.2696

• Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies

  Nature Medicine · 2012 · https://doi.org/10.1038/nm.2673

• Breast Cancer Molecular Subtypes Respond Differently to Preoperative Chemotherapy

  Clinical Cancer Research · 2005 · 10.1158/1078-0432.ccr-04-2421

Current projects

No projects listed.