Richard S. Houlston

Research interests

Publications

• Lung adenocarcinoma promotion by air pollutants

  Nature · 2023 · https://doi.org/10.1038/s41586-023-05874-3

• Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic

  Annals of Oncology · 2020 · https://doi.org/10.1016/j.annonc.2020.05.009

• Effect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study

  The Lancet Oncology · 2020 · https://doi.org/10.1016/s1470-2045(20)30392-2

• Genetic predisposition to mosaic Y chromosome loss in blood

  Nature · 2019 · https://doi.org/10.1038/s41586-019-1765-3

• Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors

  Nature Genetics · 2017 · https://doi.org/10.1038/ng.3823

• Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.3002

• Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2503

• A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma

  The American Journal of Human Genetics · 2011 · https://doi.org/10.1016/j.ajhg.2011.05.003

• A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.668

• Genome-wide association study identifies five new breast cancer susceptibility loci

  Nature Genetics · 2010 · 10.1038/ng.586

• A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma

  The American Journal of Human Genetics · 2009 · https://doi.org/10.1016/j.ajhg.2009.09.012

• The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.406

• Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia

  Nature Genetics · 2009 · 10.1038/ng.430

• A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.424

• Genome-wide association study identifies five susceptibility loci for glioma

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.407

• A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

  Nature Genetics · 2008 · https://doi.org/10.1038/ng.111

• Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21

  Nature Genetics · 2008 · https://doi.org/10.1038/ng.133

• Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

  Nature Genetics · 2008 · https://doi.org/10.1038/ng.109

• Common 5p15.33 and 6p21.33 variants influence lung cancer risk

  Nature Genetics · 2008 · 10.1038/ng.273

• A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk

  Nature Genetics · 2007 · 10.1038/ng.2007.18

• A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21

  Nature Genetics · 2007 · 10.1038/ng2085

• Frequency and Spectrum of Cancers in the Peutz-Jeghers Syndrome

  Clinical Cancer Research · 2006 · https://doi.org/10.1158/1078-0432.ccr-06-0083

• Diagnostic criteria for monoclonal B‐cell lymphocytosis

  British Journal of Haematology · 2005 · https://doi.org/10.1111/j.1365-2141.2005.05550.x

• Systematic Review of Microsatellite Instability and Colorectal Cancer Prognosis

  Journal of Clinical Oncology · 2005 · https://doi.org/10.1200/jco.2005.01.086

• Thymidylate Synthase Expression and Prognosis in Colorectal Cancer: A Systematic Review and Meta-Analysis

  Journal of Clinical Oncology · 2004 · https://doi.org/10.1200/jco.2004.05.064

• Mutations in PTF1A cause pancreatic and cerebellar agenesis

  Nature Genetics · 2004 · 10.1038/ng1475

• Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

  Nature Genetics · 2002 · https://doi.org/10.1038/ng849

• Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations

  Nature Genetics · 2002 · https://doi.org/10.1038/ng879

• A systematic review and meta-analysis of familial colorectal cancer risk

  The American Journal of Gastroenterology · 2001 · 10.1111/j.1572-0241.2001.04677.x

• Mutations in the SMAD4/DPC4 Gene in Juvenile Polyposis

  Science · 1998 · https://doi.org/10.1126/science.280.5366.1086

Current projects

No projects listed.