David E. Neal

Research interests

Publications

• Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

  Nature Genetics · 2023 · https://doi.org/10.1038/s41588-023-01534-4

• Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer

  New England Journal of Medicine · 2023 · https://doi.org/10.1056/nejmoa2214122

• Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

  Nature Genetics · 2021 · https://doi.org/10.1038/s41588-020-00748-0

• Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0142-8

• Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

  BMJ · 2018 · https://doi.org/10.1136/bmj.j5757

• 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer

  New England Journal of Medicine · 2016 · https://doi.org/10.1056/nejmoa1606220

• Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer

  New England Journal of Medicine · 2016 · https://doi.org/10.1056/nejmoa1606221

• Mutational signatures of ionizing radiation in second malignancies

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms12605

• Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

  Cancer Discovery · 2016 · https://doi.org/10.1158/2159-8290.cd-15-1227

• Predicting High-Grade Cancer at Ten-Core Prostate Biopsy Using Four Kallikrein Markers Measured in Blood in the ProtecT Study

  JNCI Journal of the National Cancer Institute · 2015 · https://doi.org/10.1093/jnci/djv095

• The evolutionary history of lethal metastatic prostate cancer

  Nature · 2015 · https://doi.org/10.1038/nature14347

• Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study

  EBioMedicine · 2015 · https://doi.org/10.1016/j.ebiom.2015.07.017

• Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study

  The Lancet Oncology · 2014 · https://doi.org/10.1016/s1470-2045(14)71021-6

• Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2560

• A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2437

• Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.882

• Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.450

• Multiple loci on 8q24 associated with prostate cancer susceptibility

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.452

• Multiple newly identified loci associated with prostate cancer susceptibility

  Nature Genetics · 2008 · https://doi.org/10.1038/ng.90

• Multiple Loci With Different Cancer Specificities Within the 8q24 Gene Desert

  JNCI Journal of the National Cancer Institute · 2008 · https://doi.org/10.1093/jnci/djn190

• Prostate Testing for Cancer and Treatment (ProtecT) feasibility study

  Health Technology Assessment · 2003 · https://doi.org/10.3310/hta7140

• Quality improvement report Improving design and conduct of randomised trials by embedding them in qualitative research: ProtecT (prostate testing for cancer and treatment) study Commentary: presenting unbiased information to patients can be difficult

  BMJ · 2002 · https://doi.org/10.1136/bmj.325.7367.766

• Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.

  PubMed · 1993

Current projects

No projects listed.