Philip J. Cowen

Research interests

Publications

• Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis

  The Lancet · 2022 · 10.1016/s0140-6736(22)00878-9

• A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials

  Molecular Psychiatry · 2021 · https://doi.org/10.1038/s41380-021-01381-x

• Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis

  The Lancet Psychiatry · 2019 · 10.1016/s2215-0366(19)30217-2

• Treatment-resistant depression and peripheral C-reactive protein

  The British Journal of Psychiatry · 2018 · https://doi.org/10.1192/bjp.2018.66

• How do antidepressants work? New perspectives for refining future treatment approaches

  The Lancet Psychiatry · 2017 · https://doi.org/10.1016/s2215-0366(17)30015-9

• What has serotonin to do with depression?

  World Psychiatry · 2015 · 10.1002/wps.20229

• Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group

  Molecular Psychiatry · 2015 · https://doi.org/10.1038/mp.2015.69

• Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2008 British Association for Psychopharmacology guidelines

  Journal of Psychopharmacology · 2015 · https://doi.org/10.1177/0269881115581093

• Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers

  Psychopharmacology · 2014 · 10.1007/s00213-014-3810-0

• Effect of Acute Antidepressant Administration on Negative Affective Bias in Depressed Patients

  American Journal of Psychiatry · 2009 · 10.1176/appi.ajp.2009.09020149

• Effect of a single dose of citalopram on amygdala response to emotional faces

  The British Journal of Psychiatry · 2009 · 10.1192/bjp.bp.108.056093

• Diminished Neural Processing of Aversive and Rewarding Stimuli During Selective Serotonin Reuptake Inhibitor Treatment

  Biological Psychiatry · 2009 · 10.1016/j.biopsych.2009.11.001

• Why do antidepressants take so long to work? A cognitive neuropsychological model of antidepressant drug action

  The British Journal of Psychiatry · 2009 · 10.1192/bjp.bp.108.051193

• Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2000 British Association for Psychopharmacology guidelines

  Journal of Psychopharmacology · 2008 · https://doi.org/10.1177/0269881107088441

• Reduction in Occipital Cortex γ-Aminobutyric Acid Concentrations in Medication-Free Recovered Unipolar Depressed and Bipolar Subjects

  Biological Psychiatry · 2007 · 10.1016/j.biopsych.2006.08.048

• Antidepressant Drug Treatment Modifies the Neural Processing of Nonconscious Threat Cues

  Biological Psychiatry · 2006 · 10.1016/j.biopsych.2005.10.015

• Increased salivary cortisol after waking in depression

  Psychopharmacology · 2005 · 10.1007/s00213-005-0062-z

• Increased Positive Versus Negative Affective Perception and Memory in Healthy Volunteers Following Selective Serotonin and Norepinephrine Reuptake Inhibition

  American Journal of Psychiatry · 2004 · 10.1176/appi.ajp.161.7.1256

• Acute SSRI Administration Affects the Processing of Social Cues in Healthy Volunteers

  Neuropsychopharmacology · 2003 · 10.1038/sj.npp.1300004

• Brain Serotonin1A Receptor Binding Measured by Positron Emission Tomography With [11C]WAY-100635

  Archives of General Psychiatry · 2000 · https://doi.org/10.1001/archpsyc.57.2.174

• Covariation of Activity in Habenula and Dorsal Raphé Nuclei Following Tryptophan Depletion

  NeuroImage · 1999 · 10.1006/nimg.1999.0455

• Relapse of depression after rapid depletion of tryptophan

  The Lancet · 1997 · 10.1016/s0140-6736(96)07044-4

• Tryptophan depletion in normal volunteers produces selective impairments in learning and memory

  Neuropharmacology · 1994 · 10.1016/0028-3908(94)90089-2

• Immunogold-silver staining: new method of immunostaining with enhanced sensitivity.

  Journal of Histochemistry & Cytochemistry · 1983 · 10.1177/31.7.6189883

• Direct radioimmunoassay for melatonin in plasma.

  Clinical Chemistry · 1983 · https://doi.org/10.1093/clinchem/29.2.396

• Unusual interactions of benzodiazepine receptor antagonists

  Nature · 1982 · https://doi.org/10.1038/295436a0

• Ethyl β-carboline carboxylate lowers seizure threshold and antagonizes flurazepam-induced sedation in rats

  Nature · 1981 · https://doi.org/10.1038/290054a0

Current projects

No projects listed.