Matthew A. Brown

Research interests

Publications

• Ankylosing spondylitis: an autoimmune or autoinflammatory disease?

  Nature Reviews Rheumatology · 2021 · https://doi.org/10.1038/s41584-021-00625-y

• Whole-genome sequencing of a sporadic primary immunodeficiency cohort

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2265-1

• Whole-genome sequencing of patients with rare diseases in a national health system

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2434-2

• Measuring the Effects of Non-Identical Data Distribution for Federated Visual Classification

  arXiv (Cornell University) · 2019 · 10.48550/arxiv.1909.06335

• Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans

  Journal of Allergy and Clinical Immunology · 2018 · https://doi.org/10.1016/j.jaci.2018.01.039

• Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

  Cell · 2018 · https://doi.org/10.1016/j.cell.2018.05.046

• Low-Shot Learning with Imprinted Weights

  · 2018 · 10.1109/cvpr.2018.00610

• 10 Years of GWAS Discovery: Biology, Function, and Translation

  The American Journal of Human Genetics · 2017 · 10.1016/j.ajhg.2017.06.005

• Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

  Nature Genetics · 2016 · 10.1038/ng.3528

• Comprehensive Rare Variant Analysis via Whole-Genome Sequencing to Determine the Molecular Pathology of Inherited Retinal Disease

  The American Journal of Human Genetics · 2016 · https://doi.org/10.1016/j.ajhg.2016.12.003

• Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

  Nature Communications · 2015 · https://doi.org/10.1038/ncomms8146

• Correction: Corrigendum: Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis

  Nature Communications · 2015 · 10.1038/ncomms8741

• Genetic insights into common pathways and complex relationships among immune-mediated diseases

  Nature Reviews Genetics · 2013 · 10.1038/nrg3502

• Genetics of rheumatoid arthritis contributes to biology and drug discovery

  Nature · 2013 · https://doi.org/10.1038/nature12873

• Efficacy and safety of adalimumab in patients with non-radiographic axial spondyloarthritis: results of a randomised placebo-controlled trial (ABILITY-1)

  Annals of the Rheumatic Diseases · 2012 · https://doi.org/10.1136/annrheumdis-2012-201766

• Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.1081

• Bayesian refinement of association signals for 14 loci in 3 common diseases

  Nature Genetics · 2012 · 10.1038/ng.2435

• Five Years of GWAS Discovery

  The American Journal of Human Genetics · 2012 · 10.1016/j.ajhg.2011.11.029

• Multi-spectral SIFT for scene category recognition

  · 2011 · 10.1109/cvpr.2011.5995637

• Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

  The Lancet · 2011 · https://doi.org/10.1016/s0140-6736(11)60874-x

• Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.873

• Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.513

• Discriminative Learning of Local Image Descriptors

  IEEE Transactions on Pattern Analysis and Machine Intelligence · 2010 · 10.1109/tpami.2010.54

• Promise and pitfalls of the Immunochip

  Arthritis Research & Therapy · 2010 · 10.1186/ar3204

• Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.483

• Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.396

• City-Scale Location Recognition

  · 2007 · 10.1109/cvpr.2007.383150

• A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

  Nature Genetics · 2006 · https://doi.org/10.1038/ng1783

• Susceptibility to ankylosing spondylitis in twins the role of genes, HLA, and the environment

  Arthritis & Rheumatism · 1997 · 10.1002/art.1780401015

• Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)

  The Lancet · 1996 · 10.1016/s0140-6736(96)90866-1

• Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction.

  Circulation · 1987 · 10.1161/01.cir.76.1.44

Current projects

No projects listed.