Peter M. Rothwell

Research interests

Publications

• Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy

  The Lancet · 2021 · https://doi.org/10.1016/s0140-6736(21)01910-3

• Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis

  The Lancet · 2021 · https://doi.org/10.1016/s0140-6736(21)00590-0

• Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis

  The Lancet · 2021 · https://doi.org/10.1016/s0140-6736(21)01921-8

• Incidence and prevalence of dementia associated with transient ischaemic attack and stroke: analysis of the population-based Oxford Vascular Study

  The Lancet Neurology · 2019 · 10.1016/s1474-4422(18)30442-3

• Effects of aspirin on risks of vascular events and cancer according to bodyweight and dose: analysis of individual patient data from randomised trials

  The Lancet · 2018 · https://doi.org/10.1016/s0140-6736(18)31133-4

• Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0058-3

• Five-Year Risk of Stroke after TIA or Minor Ischemic Stroke

  New England Journal of Medicine · 2018 · https://doi.org/10.1056/nejmoa1802712

• Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial

  The Lancet · 2018 · 10.1016/s0140-6736(18)31924-x

• One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke

  New England Journal of Medicine · 2016 · https://doi.org/10.1056/nejmoa1412981

• Meta-analysis of Genome-wide Association Studies Identifies 1q22 as a Susceptibility Locus for Intracerebral Hemorrhage

  The American Journal of Human Genetics · 2014 · https://doi.org/10.1016/j.ajhg.2014.02.012

• Population-Based Study of Incidence and Outcome of Acute Aortic Dissection and Premorbid Risk Factor Control

  Circulation · 2013 · 10.1161/circulationaha.112.000483

• Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.1081

• Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials

  The Lancet Oncology · 2012 · 10.1016/s1470-2045(12)70112-2

• Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials

  The Lancet · 2012 · 10.1016/s0140-6736(12)60209-8

• Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials

  The Lancet · 2012 · 10.1016/s0140-6736(11)61720-0

• Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials

  The Lancet · 2010 · 10.1016/s0140-6736(10)61543-7

• Prognostic significance of visit-to-visit variability, maximum systolic blood pressure, and episodic hypertension

  The Lancet · 2010 · 10.1016/s0140-6736(10)60308-x

• Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials

  The Lancet · 2010 · 10.1016/s0140-6736(10)62110-1

• Effects of antihypertensive-drug class on interindividual variation in blood pressure and risk of stroke: a systematic review and meta-analysis

  The Lancet · 2010 · 10.1016/s0140-6736(10)60235-8

• Limitations of the usual blood-pressure hypothesis and importance of variability, instability, and episodic hypertension

  The Lancet · 2010 · 10.1016/s0140-6736(10)60309-1

• Effects of β blockers and calcium-channel blockers on within-individual variability in blood pressure and risk of stroke

  The Lancet Neurology · 2010 · 10.1016/s1474-4422(10)70066-1

• Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis

  The Lancet Neurology · 2009 · 10.1016/s1474-4422(09)70236-4

• Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack

  The Lancet · 2007 · 10.1016/s0140-6736(07)60150-0

• Risk of stroke early after transient ischaemic attack: a systematic review and meta-analysis

  The Lancet Neurology · 2007 · 10.1016/s1474-4422(07)70274-0

• Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials

  The Lancet Neurology · 2007 · https://doi.org/10.1016/s1474-4422(07)70036-4

• Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison

  The Lancet · 2007 · 10.1016/s0140-6736(07)61448-2

• Subgroup analysis in randomised controlled trials: importance, indications, and interpretation

  The Lancet · 2005 · 10.1016/s0140-6736(05)17709-5

• External validity of randomised controlled trials: “To whom do the results of this trial apply?”

  The Lancet · 2005 · 10.1016/s0140-6736(04)17670-8

• Population based study of early risk of stroke after transient ischaemic attack or minor stroke: implications for public education and organisation of services

  BMJ · 2004 · 10.1136/bmj.37991.635266.44

• Early risk of recurrence by subtype of ischemic stroke in population-based incidence studies

  Neurology · 2004 · 10.1212/01.wnl.0000110311.09970.83

• Doctors and patients don't agree: cross sectional study of patients' and doctors' perceptions and assessments of disability in multiple sclerosis

  BMJ · 1997 · 10.1136/bmj.314.7094.1580

Current projects

No projects listed.