Christopher E. Brightling

Research interests

Publications

• Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study

  The Lancet Respiratory Medicine · 2022 · https://doi.org/10.1016/s2213-2600(22)00127-8

• Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge

  EClinicalMedicine · 2021 · https://doi.org/10.1016/j.eclinm.2020.100683

• Management of hospitalised adults with coronavirus disease 2019 (COVID-19): a European Respiratory Society living guideline

  European Respiratory Journal · 2021 · https://doi.org/10.1183/13993003.00048-2021

• Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study

  The Lancet Respiratory Medicine · 2021 · https://doi.org/10.1016/s2213-2600(21)00383-0

• Inflammatory Endotype–associated Airway Microbiome in Chronic Obstructive Pulmonary Disease Clinical Stability and Exacerbations: A Multicohort Longitudinal Analysis

  American Journal of Respiratory and Critical Care Medicine · 2020 · https://doi.org/10.1164/rccm.202009-3448oc

• Dexamethasone in Hospitalized Patients with Covid-19.

  DiRROS repository (University of Maribor) · 2020 · https://doi.org/10.17863/cam.57006

• Benralizumab for the Prevention of COPD Exacerbations

  New England Journal of Medicine · 2019 · https://doi.org/10.1056/nejmoa1905248

• Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline

  European Respiratory Journal · 2019 · https://doi.org/10.1183/13993003.00588-2019

• Exploring the relevance and extent of small airways dysfunction in asthma (ATLANTIS): baseline data from a prospective cohort study

  The Lancet Respiratory Medicine · 2019 · https://doi.org/10.1016/s2213-2600(19)30049-9

• Classification of Cough as a Symptom in Adults and Management Algorithms

  CHEST Journal · 2017 · https://doi.org/10.1016/j.chest.2017.10.016

• Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

  Nature Genetics · 2017 · https://doi.org/10.1038/s41588-017-0014-7

• Asthma

  The Lancet · 2017 · https://doi.org/10.1016/s0140-6736(17)33311-1

• Comorbidity in severe asthma requiring systemic corticosteroid therapy: cross-sectional data from the Optimum Patient Care Research Database and the British Thoracic Difficult Asthma Registry

  Thorax · 2016 · https://doi.org/10.1136/thoraxjnl-2015-207630

• MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis

  Journal of Allergy and Clinical Immunology · 2016 · https://doi.org/10.1016/j.jaci.2016.03.025

• ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle

  Clinical and Translational Allergy · 2016 · https://doi.org/10.1186/s13601-016-0137-4

• Treatment of Unexplained Chronic Cough

  CHEST Journal · 2015 · https://doi.org/10.1378/chest.15-1496

• Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial

  The Lancet Respiratory Medicine · 2015 · https://doi.org/10.1016/s2213-2600(15)00197-6

• Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease

  Journal of Allergy and Clinical Immunology · 2015 · https://doi.org/10.1016/j.jaci.2015.01.046

• MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation

  Allergy · 2015 · https://doi.org/10.1111/all.12686

• Eosinophilic inflammation in COPD: prevalence and clinical characteristics

  European Respiratory Journal · 2014 · https://doi.org/10.1183/09031936.00162414

• Integrated care pathways for airway diseases (AIRWAYS-ICPs)

  European Respiratory Journal · 2014 · https://doi.org/10.1183/09031936.00014614

• International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

  European Respiratory Journal · 2013 · https://doi.org/10.1183/09031936.00202013

• Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs

  Journal of Allergy and Clinical Immunology · 2012 · https://doi.org/10.1016/j.jaci.2012.07.053

• Systems medicine and integrated care to combat chronic noncommunicable diseases

  Genome Medicine · 2011 · https://doi.org/10.1186/gm259

• Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma

  Journal of Allergy and Clinical Immunology · 2010 · https://doi.org/10.1016/j.jaci.2010.07.019

• Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma

  New England Journal of Medicine · 2009 · https://doi.org/10.1056/nejmoa0808991

• Cluster Analysis and Clinical Asthma Phenotypes

  American Journal of Respiratory and Critical Care Medicine · 2008 · https://doi.org/10.1164/rccm.200711-1754oc

Current projects

No projects listed.