Freddie C. Hamdy

Research interests

Publications

• Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer

  New England Journal of Medicine · 2023 · https://doi.org/10.1056/nejmoa2214122

• Spatially resolved clonal copy number alterations in benign and malignant tissue

  Nature · 2022 · https://doi.org/10.1038/s41586-022-05023-2

• Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

  Nature Genetics · 2021 · https://doi.org/10.1038/s41588-020-00748-0

• Negative Predictive Value of Multiparametric Magnetic Resonance Imaging in the Detection of Clinically Significant Prostate Cancer in the Prostate Imaging Reporting and Data System Era: A Systematic Review and Meta-analysis

  European Urology · 2020 · 10.1016/j.eururo.2020.03.048

• Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality

  JAMA · 2018 · 10.1001/jama.2018.0154

• Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0142-8

• 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer

  New England Journal of Medicine · 2016 · https://doi.org/10.1056/nejmoa1606220

• Mutational signatures of ionizing radiation in second malignancies

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms12605

• Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer

  New England Journal of Medicine · 2016 · https://doi.org/10.1056/nejmoa1606221

• Prevention and early detection of prostate cancer

  The Lancet Oncology · 2014 · https://doi.org/10.1016/s1470-2045(14)70211-6

• Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2560

• Mre11-Dependent Degradation of Stalled DNA Replication Forks Is Prevented by BRCA2 and PARP1

  Cancer Research · 2012 · 10.1158/0008-5472.can-11-3417

• Changes in circulating microRNA levels associated with prostate cancer

  British Journal of Cancer · 2012 · 10.1038/bjc.2011.595

• MicroRNA in Prostate, Bladder, and Kidney Cancer: A Systematic Review

  European Urology · 2011 · https://doi.org/10.1016/j.eururo.2011.01.044

• A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

  Nature Genetics · 2011 · 10.1038/ng.926

• Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.882

• High Aldehyde Dehydrogenase Activity Identifies Tumor-Initiating and Metastasis-Initiating Cells in Human Prostate Cancer

  Cancer Research · 2010 · 10.1158/0008-5472.can-09-3806

• Multiple loci on 8q24 associated with prostate cancer susceptibility

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.452

• Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.450

• Distinct MicroRNA Alterations Characterize High- and Low-Grade Bladder Cancer

  Cancer Research · 2009 · 10.1158/0008-5472.can-09-0744

• Multiple newly identified loci associated with prostate cancer susceptibility

  Nature Genetics · 2008 · https://doi.org/10.1038/ng.90

• Multiple Loci With Different Cancer Specificities Within the 8q24 Gene Desert

  JNCI Journal of the National Cancer Institute · 2008 · https://doi.org/10.1093/jnci/djn190

• Promoter Hypermethylation Is Associated With Tumor Location, Stage, and Subsequent Progression in Transitional Cell Carcinoma

  Journal of Clinical Oncology · 2005 · 10.1200/jco.2005.03.163

• Use of Prostate-Specific Antigen (PSA) Isoforms for the Detection of Prostate Cancer in Men with a PSA Level of 2–10 ng/ml: Systematic Review and Meta-Analysis

  European Urology · 2005 · 10.1016/j.eururo.2005.04.015

• Quality improvement report Improving design and conduct of randomised trials by embedding them in qualitative research: ProtecT (prostate testing for cancer and treatment) study Commentary: presenting unbiased information to patients can be difficult

  BMJ · 2002 · https://doi.org/10.1136/bmj.325.7367.766

• Comparison of phytotherapy (Permixon®) with finasteride in the treatment of benign prostate hyperplasia: A randomized international study of 1,098 patients

  The Prostate · 1996 · 10.1002/(sici)1097-0045(199610)29:4<231::aid-pros4>3.0.co;2-e

Current projects

No projects listed.