Ralf Kubitz

Research interests

Publications

• Phenotypic spectrum and diagnostic pitfalls of ABCB4 deficiency depending on age of onset

  Hepatology Communications · 2018 · https://doi.org/10.1002/hep4.1149

• Sequencing of FIC1, BSEP and MDR3 in a large cohort of patients with cholestasis revealed a high number of different genetic variants

  Journal of Hepatology · 2017 · 10.1016/j.jhep.2017.07.004

• TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro

  Gut · 2015 · https://doi.org/10.1136/gutjnl-2015-309458

• Conjugated bilirubin triggers anemia by inducing erythrocyte death

  Hepatology · 2014 · https://doi.org/10.1002/hep.27338

• Strategies to Inhibit Entry of HBV and HDV Into Hepatocytes

  Gastroenterology · 2014 · https://doi.org/10.1053/j.gastro.2014.04.030

• Hepatitis B and D Viruses Exploit Sodium Taurocholate Co-transporting Polypeptide for Species-Specific Entry into Hepatocytes

  Gastroenterology · 2013 · https://doi.org/10.1053/j.gastro.2013.12.024

• A Comprehensive Analysis of Common Genetic Variation Around Six Candidate Loci for Intrahepatic Cholestasis of Pregnancy

  The American Journal of Gastroenterology · 2013 · 10.1038/ajg.2013.406

• The bile salt export pump (BSEP) in health and disease

  Clinics and Research in Hepatology and Gastroenterology · 2012 · https://doi.org/10.1016/j.clinre.2012.06.006

• Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians

  Hepatology · 2010 · https://doi.org/10.1002/hep.24017

• The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders #

  Hepatology · 2009 · https://doi.org/10.1002/hep.23032

• De novo bile salt transporter antibodies as a possible cause of recurrent graft failure after liver transplantation

  Hepatology · 2009 · 10.1002/hep.23083

• Expression and function of the bile acid receptor TGR5 in Kupffer cells

  Biochemical and Biophysical Research Communications · 2008 · https://doi.org/10.1016/j.bbrc.2008.04.171

• Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy

  Gut · 2008 · https://doi.org/10.1136/gut.2008.159541

• A mutation in the canalicular phospholipid transporter gene, ABCB4, is associated with cholestasis, ductopenia, and cirrhosis in adults†‡

  Hepatology · 2008 · 10.1002/hep.22485

• Endocrine and paracrine role of bile acids

  World Journal of Gastroenterology · 2008 · 10.3748/wjg.14.5620

• The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells

  Hepatology · 2007 · https://doi.org/10.1002/hep.21458

• Combined Mutations of Canalicular Transporter Proteins Cause Severe Intrahepatic Cholestasis of Pregnancy

  Gastroenterology · 2006 · https://doi.org/10.1053/j.gastro.2006.05.003

• Expression in Human Trophoblast and Choriocarcinoma Cell Lines, BeWo, Jeg-3 and JAr of Genes Involved in the Hepatobiliary-like Excretory Function of the Placenta

  Placenta · 2006 · 10.1016/j.placenta.2006.03.009

• Expression and localization of hepatobiliary transport proteins in progressive familial intrahepatic cholestasis†

  Hepatology · 2005 · https://doi.org/10.1002/hep.20682

• Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase

  Gastroenterology · 2004 · 10.1053/j.gastro.2003.11.003

• Protein Kinase C-Dependent Distribution of the Multidrug Resistance Protein 2 From the Canalicular to the Basolateral Membrane in Human Hepg2 Cells

  Hepatology · 2001 · 10.1053/jhep.2001.25959

• Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone

  Gastroenterology · 1999 · https://doi.org/10.1016/s0016-5085(99)70138-1

• Osmodependent dynamic localization of the multidrug resistance protein 2 in the rat hepatocyte canalicular membrane

  Gastroenterology · 1997 · 10.1053/gast.1997.v113.pm9352844

Current projects

No projects listed.