Albert C. Ludolph

Research interests

Publications

• Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial

  Nature Medicine · 2023 · 10.1038/s41591-023-02326-3

• Blood GFAP as an emerging biomarker in brain and spinal cord disorders

  Nature Reviews Neurology · 2022 · 10.1038/s41582-021-00616-3

• Nusinersen in adults with 5q spinal muscular atrophy: a non-interventional, multicentre, observational cohort study

  The Lancet Neurology · 2020 · 10.1016/s1474-4422(20)30037-5

• Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation

  Nature Communications · 2018 · 10.1038/s41467-017-02299-1

• Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model

  The Lancet Neurology · 2018 · 10.1016/s1474-4422(18)30089-9

• Glial Fibrillary Acidic Protein in Serum is Increased in Alzheimer’s Disease and Correlates with Cognitive Impairment

  Journal of Alzheimer s Disease · 2018 · https://doi.org/10.3233/jad-180325

• Neurofilament light chain in serum for the diagnosis of amyotrophic lateral sclerosis

  Journal of Neurology Neurosurgery & Psychiatry · 2018 · 10.1136/jnnp-2018-318704

• NEK1 variants confer susceptibility to amyotrophic lateral sclerosis

  Nature Genetics · 2016 · 10.1038/ng.3626

• Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

  Nature Neuroscience · 2015 · https://doi.org/10.1038/nn.4000

• A revision of the El Escorial criteria - 2015

  Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration · 2015 · 10.3109/21678421.2015.1049183

• TDP-43 is intercellularly transmitted across axon terminals

  The Journal of Cell Biology · 2015 · 10.1083/jcb.201504057

• Neurofilaments in the diagnosis of motoneuron diseases: a prospective study on 455 patients

  Journal of Neurology Neurosurgery & Psychiatry · 2015 · 10.1136/jnnp-2015-311387

• TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord

  Acta Neuropathologica · 2014 · 10.1007/s00401-014-1299-6

• Inflammatory dysregulation of blood monocytes in Parkinson’s disease patients

  Acta Neuropathologica · 2014 · 10.1007/s00401-014-1345-4

• Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD)

  Acta Neuropathologica · 2014 · 10.1007/s00401-013-1238-y

• Amyotrophic lateral sclerosis—a model of corticofugal axonal spread

  Nature Reviews Neurology · 2013 · 10.1038/nrneurol.2013.221

• Stages of pTDP‐43 pathology in amyotrophic lateral sclerosis

  Annals of Neurology · 2013 · 10.1002/ana.23937

• Leitlinien für Diagnostik und Therapie in der Neurologie

  Journal · 2012 · https://doi.org/10.1055/b-002-37755

• A yeast functional screen predicts new candidate ALS disease genes

  Proceedings of the National Academy of Sciences · 2011 · 10.1073/pnas.1109434108

• Guidelines for preclinical animal research in ALS/MND: A consensus meeting

  Amyotrophic Lateral Sclerosis · 2010 · 10.3109/17482960903545334

• Energy metabolism in amyotrophic lateral sclerosis

  The Lancet Neurology · 2010 · 10.1016/s1474-4422(10)70224-6

• Cognitive impairment in patients with multiple system atrophy and progressive supranuclear palsy

  Brain · 2010 · 10.1093/brain/awq158

• Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis

  Nature Genetics · 2009 · 10.1038/ng.442

• Point mutations of the p150 subunit of dynactin ( DCTN1 ) gene in ALS

  Neurology · 2004 · 10.1212/01.wnl.0000134608.83927.b1

• Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Linked to a Plant Excitant Neurotoxin

  Science · 1987 · https://doi.org/10.1126/science.3603037

Current projects

No projects listed.