W. Dekant

Research interests

Publications

• The BlueScreen HC assay to predict the genotoxic potential of fragrance materials

  Mutagenesis · 2022 · 10.1093/mutage/geac004

• The role of hazard- and risk-based approaches in ensuring food safety

  Trends in Food Science & Technology · 2015 · 10.1016/j.tifs.2015.10.007

• Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics

  Toxicology in Vitro · 2014 · 10.1016/j.tiv.2014.10.006

• Criteria for the Research Institute for Fragrance Materials, Inc. (RIFM) safety evaluation process for fragrance ingredients

  Food and Chemical Toxicology · 2014 · https://doi.org/10.1016/j.fct.2014.11.014

• Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress

  Journal of Proteomics · 2012 · https://doi.org/10.1016/j.jprot.2012.11.022

• Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010

  Archives of Toxicology · 2011 · https://doi.org/10.1007/s00204-011-0693-2

• Evaluation of a urinary kidney biomarker panel in rat models of acute and subchronic nephrotoxicity

  Toxicology · 2010 · 10.1016/j.tox.2010.08.013

• Comparative Analysis of Novel Noninvasive Renal Biomarkers and Metabonomic Changes in a Rat Model of Gentamicin Nephrotoxicity

  Toxicological Sciences · 2009 · 10.1093/toxsci/kfp070

• SCCP (Scientific Committee on Consumer Products) / SCHER (Scientific Committee on Health& Environment Risks) / SCENIHR (Scientific Committee on Emerging and Newly- Identified Health Risks) opinion on: Risk assessment methodologies and approaches for genotoxic and carcinogenic substances

  Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles) · 2009

• Evaluation of Putative Biomarkers of Nephrotoxicity after Exposure to Ochratoxin A In Vivo and In Vitro

  Toxicological Sciences · 2008 · 10.1093/toxsci/kfn040

• Human exposure to bisphenol A by biomonitoring: Methods, results and assessment of environmental exposures

  Toxicology and Applied Pharmacology · 2008 · 10.1016/j.taap.2007.12.008

• Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH)

  Archives of Toxicology · 2008 · 10.1007/s00204-008-0279-9

• Endocrine effects of tetrabromobisphenol-A (TBBPA) in Wistar rats as tested in a one-generation reproduction study and a subacute toxicity study

  Toxicology · 2007 · 10.1016/j.tox.2007.12.009

• Exposure of an Adult Population to Perfluorinated Substances Using Duplicate Diet Portions and Biomonitoring Data

  Environmental Science & Technology · 2007 · 10.1021/es071244n

• Scientific Committee on Health and Environmental Risks opinion on: The revised chapter for Human Health Risk Characterisation of the Technical Guidance Document on Risk Assessment in support of Directive 93/67/EEC on new notified substances and Regulation 1488/94 on existing substances of new and existing substances (Draft of November 2005) Members ot the Working Group of SCHER by alph

  Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles) · 2006

• Toxicokinetics of Tetrabromobisphenol A in Humans and Rats after Oral Administration

  Toxicological Sciences · 2006 · 10.1093/toxsci/kfj132

• QUANTITATION OF BISPHENOL A AND BISPHENOL A GLUCURONIDE IN BIOLOGICAL SAMPLES BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY

  Drug Metabolism and Disposition · 2005 · 10.1124/dmd.105.005454

• Metabolism and Kinetics of Bisphenol A in Humans at Low Doses Following Oral Administration

  Chemical Research in Toxicology · 2002 · 10.1021/tx025548t

• Assaying the estrogenicity of phytoestrogens in cells of different estrogen sensitive tissues

  Toxicology in Vitro · 2001 · 10.1016/s0887-2333(01)00048-0

• Occurrence of Emodin, Chrysophanol and Physcion in Vegetables, Herbs and Liquors. Genotoxicity and Anti-genotoxicity of the Anthraquinones and of the Whole Plants

  Food and Chemical Toxicology · 1999 · 10.1016/s0278-6915(99)00027-7

• GLUTATHIONE-DEPENDENT BIOACTIVATION OF HALOALKENES

  The Annual Review of Pharmacology and Toxicology · 1998 · 10.1146/annurev.pharmtox.38.1.501

• Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene

  Archives of Toxicology · 1995 · 10.1007/s002040050173

• Bioactivation of Nephrotoxic Haloalkenes by Glutathione Conjugation: Formation of Toxic and Mutagenic Intermediates by Cysteine Conjugate β-Lyase

  Drug Metabolism Reviews · 1989 · 10.3109/03602538908994144

• Biosynthesis and biotransformation of glutathione S -Conjugates to toxic metabolites

  Critical Reviews in Toxicology · 1988 · 10.3109/10408448809037470

• Bacterial β-lyase mediated cleavage and mutagenicity of cysteine conjugates derived from the nephrocarcinogenic alkenes trichloroethylene, tetrachloroethylene and hexachlorobutadiene

  Chemico-Biological Interactions · 1986 · 10.1016/0009-2797(86)90015-3

Current projects

No projects listed.