Bodo Grimbacher

Research interests

Publications

• Autoantibodies against type I IFNs in patients with critical influenza pneumonia

  The Journal of Experimental Medicine · 2022 · https://doi.org/10.1084/jem.20220514

• Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome

  Journal of Allergy and Clinical Immunology · 2022 · https://doi.org/10.1016/j.jaci.2022.09.002

• Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations

  Journal of Allergy and Clinical Immunology · 2021 · https://doi.org/10.1016/j.jaci.2021.04.015

• The European Society for Immunodeficiencies (ESID) Registry Working Definitions for the Clinical Diagnosis of Inborn Errors of Immunity

  The Journal of Allergy and Clinical Immunology In Practice · 2019 · https://doi.org/10.1016/j.jaip.2019.02.004

• A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity

  Science Immunology · 2018 · https://doi.org/10.1126/sciimmunol.aat4956

• Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects

  Journal of Allergy and Clinical Immunology · 2018 · https://doi.org/10.1016/j.jaci.2018.02.055

• Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype

  Blood · 2016 · https://doi.org/10.1182/blood-2015-11-679902

• DOCK8 Deficiency: Clinical and Immunological Phenotype and Treatment Options - a Review of 136 Patients

  Journal of Clinical Immunology · 2015 · https://doi.org/10.1007/s10875-014-0126-0

• Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations

  Nature Medicine · 2014 · https://doi.org/10.1038/nm.3746

• Clinical picture and treatment of 2212 patients with common variable immunodeficiency

  Journal of Allergy and Clinical Immunology · 2014 · https://doi.org/10.1016/j.jaci.2013.12.1077

• B-cell biology and development

  Journal of Allergy and Clinical Immunology · 2013 · https://doi.org/10.1016/j.jaci.2013.01.046

• Deleterious Mutations in LRBA Are Associated with a Syndrome of Immune Deficiency and Autoimmunity

  The American Journal of Human Genetics · 2012 · https://doi.org/10.1016/j.ajhg.2012.04.015

• Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome

  Journal of Allergy and Clinical Immunology · 2010 · https://doi.org/10.1016/j.jaci.2009.10.059

• A Homozygous CARD9 Mutation in a Family with Susceptibility to Fungal Infections

  New England Journal of Medicine · 2009 · 10.1056/nejmoa0810719

• Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

  New England Journal of Medicine · 2009 · https://doi.org/10.1056/nejmoa0907206

• Thalassemia Syndromes

  Journal · 2009 · https://doi.org/10.1007/978-3-540-29676-8_1731

• Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

  The Journal of Experimental Medicine · 2008 · https://doi.org/10.1084/jem.20080218

• Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes

  Blood · 2008 · https://doi.org/10.1182/blood-2008-02-141937

• Common variable immunodeficiency disorders: division into distinct clinical phenotypes

  Blood · 2008 · https://doi.org/10.1182/blood-2007-11-124545

• STAT3 Mutations in the Hyper-IgE Syndrome

  New England Journal of Medicine · 2007 · https://doi.org/10.1056/nejmoa073687

• An Antibody-Deficiency Syndrome Due to Mutations in theCD19Gene

  New England Journal of Medicine · 2006 · https://doi.org/10.1056/nejmoa051568

• Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans

  Nature Genetics · 2005 · https://doi.org/10.1038/ng1600

• Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency

  Nature Immunology · 2003 · https://doi.org/10.1038/ni902

• Hyper-IgE Syndrome with Recurrent Infections — An Autosomal Dominant Multisystem Disorder

  New England Journal of Medicine · 1999 · https://doi.org/10.1056/nejm199903043400904

Current projects

No projects listed.