Matthias W. Beckmann

Research interests

Publications

• Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

  Nature Genetics · 2020 · https://doi.org/10.1038/s41588-020-0609-2

• Identification of nine new susceptibility loci for endometrial cancer

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-05427-7

• Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

  The American Journal of Human Genetics · 2018 · https://doi.org/10.1016/j.ajhg.2018.11.002

• A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0132-x

• Dose-Response Association of CD8 + Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer

  JAMA Oncology · 2017 · https://doi.org/10.1001/jamaoncol.2017.3290

• Neoadjuvant trastuzumab, pertuzumab, and chemotherapy versus trastuzumab emtansine plus pertuzumab in patients with HER2-positive breast cancer (KRISTINE): a randomised, open-label, multicentre, phase 3 trial

  The Lancet Oncology · 2017 · https://doi.org/10.1016/s1470-2045(17)30716-7

• Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

  Nature Genetics · 2017 · https://doi.org/10.1038/ng.3785

• PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

  Journal of Medical Genetics · 2016 · https://doi.org/10.1136/jmedgenet-2016-103839

• Ninety-five orthotopic transplantations in 74 women of ovarian tissue after cytotoxic treatment in a fertility preservation network: tissue activity, pregnancy and delivery rates

  Human Reproduction · 2016 · https://doi.org/10.1093/humrep/dew165

• DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms10478

• Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

  PLoS ONE · 2015 · https://doi.org/10.1371/journal.pone.0128106

• The Contributions of Breast Density and Common Genetic Variation to Breast Cancer Risk

  JNCI Journal of the National Cancer Institute · 2015 · https://doi.org/10.1093/jnci/dju397

• Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

  Cell · 2015 · https://doi.org/10.1016/j.cell.2015.07.011

• Circulating Tumor Cells Predict Survival in Early Average-to-High Risk Breast Cancer Patients

  JNCI Journal of the National Cancer Institute · 2014 · https://doi.org/10.1093/jnci/dju066

• ABCA Transporter Gene Expression and Poor Outcome in Epithelial Ovarian Cancer

  JNCI Journal of the National Cancer Institute · 2014 · https://doi.org/10.1093/jnci/dju149

• GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2564

• Circulating Micro-RNAs as Potential Blood-Based Markers for Early Stage Breast Cancer Detection

  PLoS ONE · 2012 · https://doi.org/10.1371/journal.pone.0029770

• Higher efficacy of letrozole in combination with trastuzumab compared to letrozole monotherapy as first-line treatment in patients with HER2-positive, hormone-receptor-positive metastatic breast cancer – Results of the eLEcTRA trial

  The Breast · 2011 · https://doi.org/10.1016/j.breast.2011.07.006

• Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment

  BMC Cancer · 2011 · https://doi.org/10.1186/1471-2407-11-486

• A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.424

• Effect of Anastrozole on Bone Mineral Density: 5-Year Results From the Anastrozole, Tamoxifen, Alone or in Combination Trial 18233230

  Journal of Clinical Oncology · 2008 · https://doi.org/10.1200/jco.2007.11.0726

• Transplacental exposure of neonates to perfluorooctanesulfonate and perfluorooctanoate: a pilot study

  International Archives of Occupational and Environmental Health · 2007 · https://doi.org/10.1007/s00420-006-0165-9

• The VCUAM (Vagina Cervix Uterus Adnex–associated Malformation) Classification: a new classification for genital malformations

  Fertility and Sterility · 2005 · https://doi.org/10.1016/j.fertnstert.2005.05.036

• Clinical aspects of Mayer–Rokitansky–Kuester–Hauser syndrome: recommendations for clinical diagnosis and staging

  Human Reproduction · 2005 · https://doi.org/10.1093/humrep/dei381

• Prothrombin and Factor V Mutations in Women with a History of Thrombosis during Pregnancy and the Puerperium

  New England Journal of Medicine · 2000 · https://doi.org/10.1056/nejm200002103420602

Current projects

No projects listed.