Osborne F. X. Almeida

Research interests

Publications

• Chronic Stress and Glucocorticoids: From Neuronal Plasticity to Neurodegeneration

  Neural Plasticity · 2016 · https://doi.org/10.1155/2016/6391686

• Selective inhibitors of the FK506-binding protein 51 by induced fit

  Nature Chemical Biology · 2014 · https://doi.org/10.1038/nchembio.1699

• Neuropathology of stress

  Acta Neuropathologica · 2013 · https://doi.org/10.1007/s00401-013-1223-5

• Stress Acts Cumulatively To Precipitate Alzheimer's Disease-Like Tau Pathology and Cognitive Deficits

  Journal of Neuroscience · 2011 · https://doi.org/10.1523/jneurosci.0730-11.2011

• Neuropsychopharmacology

  Journal · 2010 · https://doi.org/10.1007/978-3-540-68706-1_4410

• Dynamic DNA methylation programs persistent adverse effects of early-life stress

  Nature Neuroscience · 2009 · https://doi.org/10.1038/nn.2436

• The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling

  Molecular Psychiatry · 2008 · https://doi.org/10.1038/mp.2008.119

• The stressed prefrontal cortex. Left? Right!

  Brain Behavior and Immunity · 2008 · https://doi.org/10.1016/j.bbi.2008.01.005

• The Prefrontal Cortex as a Key Target of the Maladaptive Response to Stress

  Journal of Neuroscience · 2007 · https://doi.org/10.1523/jneurosci.4372-06.2007

• A hitchhiker's guide to behavioral analysis in laboratory rodents

  Genes Brain & Behavior · 2006 · https://doi.org/10.1111/j.1601-183x.2006.00228.x

• Morphological Correlates of Corticosteroid-Induced Changes in Prefrontal Cortex-Dependent Behaviors

  Journal of Neuroscience · 2005 · https://doi.org/10.1523/jneurosci.1598-05.2005

• Soluble β-Amyloid1-40Induces NMDA-Dependent Degradation of Postsynaptic Density-95 at Glutamatergic Synapses

  Journal of Neuroscience · 2005 · https://doi.org/10.1523/jneurosci.3034-05.2005

• Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation

  Molecular Psychiatry · 2005 · https://doi.org/10.1038/sj.mp.4001679

• Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement

  Neuroscience · 2000 · https://doi.org/10.1016/s0306-4522(00)00050-6

• Subtle shifts in the ratio between pro‐ and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fate

  The FASEB Journal · 2000 · https://doi.org/10.1096/fasebj.14.5.779

• Implications of estrogen‐dependent brain organization for gender differences in hypothalamo‐pituitary‐adrenal regulation

  The FASEB Journal · 1995 · https://doi.org/10.1096/fasebj.9.5.7896013

• The neurosteroid tetrahydroprogesterone counteracts corticotropin-releasing hormone-induced anxiety and alters the release and gene expression of corticotropin-releasing hormone in the rat hypothalamus

  Neuroscience · 1994 · https://doi.org/10.1016/0306-4522(94)90330-1

• Melatonin: A Coordinating Signal for Mammalian Reproduction?

  Science · 1985 · https://doi.org/10.1126/science.3881822

Current projects

No projects listed.