Klaus‐Michael Debatin

Research interests

Publications

• Apoptotic cell death in disease—Current understanding of the NCCD 2023

  Cell Death and Differentiation · 2023 · https://doi.org/10.1038/s41418-023-01153-w

• Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

  Cell Death and Differentiation · 2018 · https://doi.org/10.1038/s41418-017-0012-4

• Childhood cancer predisposition syndromes—A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology

  American Journal of Medical Genetics Part A · 2017 · https://doi.org/10.1002/ajmg.a.38142

• Apoptosis pathways in cancer and cancer therapy

  Cancer Immunology Immunotherapy · 2004 · https://doi.org/10.1007/s00262-003-0474-8

• Death receptors in chemotherapy and cancer

  Oncogene · 2004 · https://doi.org/10.1038/sj.onc.1207558

• Chemotherapy: targeting the mitochondrial cell death pathway

  Oncogene · 2002 · https://doi.org/10.1038/sj.onc.1206039

• Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo

  Nature Medicine · 2002 · 10.1038/nm735

• Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

  Oncogene · 2001 · https://doi.org/10.1038/sj.onc.1204750

• Cellular stress response and apoptosis in cancer therapy

  Blood · 2001 · https://doi.org/10.1182/blood.v98.9.2603

• CD95 Ligand (Fas-L/APO-1L) and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Mediate Ischemia-Induced Apoptosis in Neurons

  Journal of Neuroscience · 1999 · https://doi.org/10.1523/jneurosci.19-10-03809.1999

• The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells.

  PubMed · 1997

• Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

  Nature Medicine · 1996 · https://doi.org/10.1038/nm0596-574

• Mutations in Fas Associated with Human Lymphoproliferative Syndrome and Autoimmunity

  Science · 1995 · https://doi.org/10.1126/science.7539157

• Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120

  Nature · 1995 · https://doi.org/10.1038/375497a0

• Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

  Nature · 1995 · https://doi.org/10.1038/373438a0

• Regulation of apoptosis in the immune system

  Current Opinion in Immunology · 1994 · https://doi.org/10.1016/0952-7915(94)90102-3

• Activation interferes with the APO-1 pathway in mature human T cells

  International Immunology · 1993 · https://doi.org/10.1093/intimm/5.6.625

• Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells.

  PubMed · 1993

• Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis

  Science · 1989 · https://doi.org/10.1126/science.2787530

Current projects

No projects listed.