Eckhard Wolf

Research interests

Publications

• Cellular and Molecular Probing of Intact Human Organs

  Cell · 2020 · 10.1016/j.cell.2020.01.030

• Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy

  Nature Medicine · 2020 · 10.1038/s41591-019-0738-2

• Consistent success in life-supporting porcine cardiac xenotransplantation

  Nature · 2018 · 10.1038/s41586-018-0765-z

• Animal models of obesity and diabetes mellitus

  Nature Reviews Endocrinology · 2018 · 10.1038/nrendo.2017.161

• Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

  Nature Communications · 2016 · 10.1038/ncomms11138

• Fine mapping of genome activation in bovine embryos by RNA sequencing

  Proceedings of the National Academy of Sciences · 2014 · 10.1073/pnas.1321569111

• Rapamycin extends murine lifespan but has limited effects on aging

  Journal of Clinical Investigation · 2013 · https://doi.org/10.1172/jci67674

• Transgenic pigs as models for translational biomedical research

  Journal of Molecular Medicine · 2010 · 10.1007/s00109-010-0610-9

• A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice

  Cell · 2009 · https://doi.org/10.1016/j.cell.2009.03.041

• The epidermal growth factor receptor ligands at a glance

  Journal of Cellular Physiology · 2008 · 10.1002/jcp.21635

• Genes involved in conceptus–endometrial interactions in ruminants: insights from reductionism and thoughts on holistic approaches

  Reproduction · 2008 · 10.1530/rep-07-0327

• Epigenetic Marking Correlates with Developmental Potential in Cloned Bovine Preimplantation Embryos

  Current Biology · 2003 · 10.1016/s0960-9822(03)00419-6

• Efficient transgenesis in farm animals by lentiviral vectors

  EMBO Reports · 2003 · 10.1038/sj.embor.7400007

• Impaired insulin secretory capacity in mice lacking a functional vitamin D receptor

  The FASEB Journal · 2003 · 10.1096/fj.02-0424fje

• The Ca2+-binding Proteins S100A8 and S100A9 Are Encoded by Novel Injury-regulated Genes

  Journal of Biological Chemistry · 2001 · 10.1074/jbc.m104871200

• Conservation of methylation reprogramming in mammalian development: Aberrant reprogramming in cloned embryos

  Proceedings of the National Academy of Sciences · 2001 · 10.1073/pnas.241522698

• Mitochondrial Distribution and Adenosine Triphosphate Content of Bovine Oocytes Before and After In Vitro Maturation: Correlation with Morphological Criteria and Developmental Capacity After In Vitro Fertilization and Culture1

  Biology of Reproduction · 2001 · 10.1095/biolreprod64.3.904

• Genome-wide, large-scale production of mutant mice by ENU mutagenesis

  Nature Genetics · 2000 · https://doi.org/10.1038/78146

• CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs

  Cell · 1999 · 10.1016/s0092-8674(00)80059-8

• A Putative Chemokine Receptor, BLR1, Directs B Cell Migration to Defined Lymphoid Organs and Specific Anatomic Compartments of the Spleen

  Cell · 1996 · https://doi.org/10.1016/s0092-8674(00)81798-5

• The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6.

  The Journal of Experimental Medicine · 1996 · 10.1084/jem.183.4.1399

• Specific Subtypes of Cutaneous Mechanoreceptors Require Neurotrophin-3 Following Peripheral Target Innervation

  Neuron · 1996 · 10.1016/s0896-6273(00)80047-1

• Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor.

  Proceedings of the National Academy of Sciences · 1995 · https://doi.org/10.1073/pnas.92.19.8856

• Disruption of the CNTF gene results in motor neuron degeneration

  Nature · 1993 · https://doi.org/10.1038/365027a0

• The genetic susceptibility to type 1 (insulin-dependent) diabetes: Analysis of the HLA-DR association

  Diabetologia · 1983 · 10.1007/bf00282704

Current projects

No projects listed.