Peter Vajkoczy

Research interests

Publications

• Fluid balance and outcome in critically ill patients with traumatic brain injury (CENTER-TBI and OzENTER-TBI): a prospective, multicentre, comparative effectiveness study

  The Lancet Neurology · 2021 · https://doi.org/10.1016/s1474-4422(21)00162-9

• Association between Cerebrovascular Reactivity Monitoring and Mortality Is Preserved When Adjusting for Baseline Admission Characteristics in Adult Traumatic Brain Injury: A CENTER-TBI Study

  Journal of Neurotrauma · 2019 · https://doi.org/10.1089/neu.2019.6808

• Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA–09): a randomised, open-label, phase 3 trial

  The Lancet · 2019 · https://doi.org/10.1016/s0140-6736(18)31791-4

• The movers and shapers in immune privilege of the CNS

  Nature Immunology · 2017 · https://doi.org/10.1038/ni.3666

• Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group

  Journal of Cerebral Blood Flow & Metabolism · 2016 · https://doi.org/10.1177/0271678x16654496

• The unruptured intracranial aneurysm treatment score

  Neurology · 2015 · https://doi.org/10.1212/wnl.0000000000001891

• MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial

  Clinical Cancer Research · 2015 · 10.1158/1078-0432.ccr-14-2737

• A Comparison of Language Mapping by Preoperative Navigated Transcranial Magnetic Stimulation and Direct Cortical Stimulation During Awake Surgery

  Neurosurgery · 2013 · 10.1227/neu.0b013e3182889e01

• Randomized Trial of Clazosentan in Patients With Aneurysmal Subarachnoid Hemorrhage Undergoing Endovascular Coiling

  Stroke · 2012 · https://doi.org/10.1161/strokeaha.111.648980

• Clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid haemorrhage undergoing surgical clipping: a randomised, double-blind, placebo-controlled phase 3 trial (CONSCIOUS-2)

  The Lancet Neurology · 2011 · https://doi.org/10.1016/s1474-4422(11)70108-9

• Preoperative Functional Mapping for Rolandic Brain Tumor Surgery: Comparison of Navigated Transcranial Magnetic Stimulation to Direct Cortical Stimulation

  Neurosurgery · 2011 · 10.1227/neu.0b013e3182181b89

• Inositol-requiring enzyme 1α is a key regulator of angiogenesis and invasion in malignant glioma

  Proceedings of the National Academy of Sciences · 2010 · 10.1073/pnas.0914072107

• Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage

  Brain · 2009 · 10.1093/brain/awp102

• Cerebral vasospasm following subarachnoid hemorrhage: time for a new world of thought

  Neurological Research · 2009 · https://doi.org/10.1179/174313209x393564

• Del-1, an Endogenous Leukocyte-Endothelial Adhesion Inhibitor, Limits Inflammatory Cell Recruitment

  Science · 2008 · 10.1126/science.1165218

• Effects of hypervolemia and hypertension on regional cerebral blood flow, intracranial pressure, and brain tissue oxygenation after subarachnoid hemorrhage*

  Critical Care Medicine · 2007 · 10.1097/01.ccm.0000275392.08410.dd

• High-Mobility Group Box 1 Activates Integrin-Dependent Homing of Endothelial Progenitor Cells

  Circulation Research · 2007 · 10.1161/01.res.0000257774.55970.f4

• Angiopoietin-2 sensitizes endothelial cells to TNF-α and has a crucial role in the induction of inflammation

  Nature Medicine · 2006 · https://doi.org/10.1038/nm1351

• Clazosentan (AXV-034343), a selective endothelin A receptor antagonist, in the prevention of cerebral vasospasm following severe aneurysmal subarachnoid hemorrhage: results of a randomized, double-blind, placebo-controlled, multicenter Phase IIa study

  Journal of neurosurgery · 2005 · https://doi.org/10.3171/jns.2005.103.1.0009

• Cathepsin L is required for endothelial progenitor cell–induced neovascularization

  Nature Medicine · 2005 · 10.1038/nm1182

• Regional cerebral blood flow monitoring in the diagnosis of delayed ischemia following aneurysmal subarachnoid hemorrhage

  Journal of neurosurgery · 2003 · https://doi.org/10.3171/jns.2003.98.6.1227

• Combined inhibition of VEGF‐ and PDGF‐signaling enforces tumor vessel regression by interfering with pericyte‐mediated endothelial cell survival mechanisms

  The FASEB Journal · 2003 · https://doi.org/10.1096/fj.03-0271fje

• α4-integrin-VCAM-1 binding mediates G protein–independent capture of encephalitogenic T cell blasts to CNS white matter microvessels

  Journal of Clinical Investigation · 2001 · 10.1172/jci12440

• Continuous monitoring of regional cerebral blood flow: experimental and clinical validation of a novel thermal diffusion microprobe

  Journal of neurosurgery · 2000 · https://doi.org/10.3171/jns.2000.93.2.0265

• SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors.

  PubMed · 2000

Current projects

No projects listed.