Michael D. Menger

Research interests

Publications

• Thermosensitive Hydrogel Based on PEO–PPO–PEO Poloxamers for a Controlled In Situ Release of Recombinant Adeno‐Associated Viral Vectors for Effective Gene Therapy of Cartilage Defects

  Advanced Materials · 2019 · 10.1002/adma.201906508

• Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation

  Nature Immunology · 2019 · 10.1038/s41590-019-0548-1

• Life is 3D: Boosting Spheroid Function for Tissue Engineering

  Trends in biotechnology · 2016 · https://doi.org/10.1016/j.tibtech.2016.08.004

• Prevascularization in tissue engineering: Current concepts and future directions

  Biotechnology Advances · 2015 · 10.1016/j.biotechadv.2015.12.004

• Vascularization in Tissue Engineering: Angiogenesis versus Inosculation

  European Surgical Research · 2012 · 10.1159/000336876

• TLR2 Is a Primary Receptor for Alzheimer’s Amyloid β Peptide To Trigger Neuroinflammatory Activation

  The Journal of Immunology · 2011 · https://doi.org/10.4049/jimmunol.1101121

• Intestinal ischemia/reperfusion: microcirculatory pathology and functional consequences

  Langenbeck s Archives of Surgery · 2010 · 10.1007/s00423-010-0727-x

• The Hepatic Microcirculation: Mechanistic Contributions and Therapeutic Targets in Liver Injury and Repair

  Physiological Reviews · 2009 · https://doi.org/10.1152/physrev.00027.2008

• In vitro and in vivo approaches to study angiogenesis in the pathophysiology and therapy of endometriosis

  Human Reproduction Update · 2007 · 10.1093/humupd/dmm006

• Angiogenic and inflammatory response to biodegradable scaffolds in dorsal skinfold chambers of mice

  Biomaterials · 2006 · 10.1016/j.biomaterials.2006.05.033

• Angiogenesis in Tissue Engineering: Breathing Life into Constructed Tissue Substitutes

  Tissue Engineering · 2006 · https://doi.org/10.1089/ten.2006.12.2093

• Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I)

  Gene Therapy · 2005 · 10.1038/sj.gt.3302515

• Improved Tissue Repair in Articular Cartilage Defects in Vivo by rAAV-Mediated Overexpression of Human Fibroblast Growth Factor 2

  Molecular Therapy · 2005 · 10.1016/j.ymthe.2005.03.012

• Surgical trauma: hyperinflammation versus immunosuppression?

  Langenbeck s Archives of Surgery · 2004 · 10.1007/s00423-004-0472-0

• Combined inhibition of VEGF‐ and PDGF‐signaling enforces tumor vessel regression by interfering with pericyte‐mediated endothelial cell survival mechanisms

  The FASEB Journal · 2003 · https://doi.org/10.1096/fj.03-0271fje

• Comparison of surgical stress between laparoscopic and open colonic resections

  Surgical Endoscopy · 2003 · 10.1007/s00464-001-9148-9

• Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2

  Journal of Clinical Investigation · 2002 · 10.1172/jci14105

• Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2

  Journal of Clinical Investigation · 2002 · 10.1172/jci0214105

• Vascular Microenvironment in Gliomas

  Journal of Neuro-Oncology · 2000 · 10.1023/a:1006474832189

• LIVER ISCHEMIA AND REPERFUSION INDUCES A SYSTEMIC INFLAMMATORY RESPONSE THROUGH KUPFFER CELL ACTIVATION

  Shock · 1996 · 10.1097/00024382-199601000-00008

• Leukocytes contribute to hepatic ischemia/reperfusion injury via intercellular adhesion molecule-1-mediated venular adherence

  Surgery · 1995 · 10.1016/s0039-6060(05)80085-6

• Hepatic microcirculatory perfusion failure is a determinant of liver dysfunction in warm ischemia-reperfusion.

  PubMed · 1994

• Scope and perspectives of intravital microscopy - bridge over from in vitro to in vivo

  Immunology Today · 1993 · 10.1016/0167-5699(93)90179-o

• Dorsal skinfold chamber technique for intravital microscopy in nude mice.

  PubMed · 1993

• Angiogenesis and Hemodynamics of Microvasculature of Transplanted Islets of Langerhans

  Diabetes · 1989 · 10.2337/diab.38.1.s199

Current projects

No projects listed.