Patrick M. Sexton

Research interests

Publications

• Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03897-2

• Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists

  Molecular Cell · 2020 · https://doi.org/10.1016/j.molcel.2020.09.020

• Mechanisms of signalling and biased agonism in G protein-coupled receptors

  Nature Reviews Molecular Cell Biology · 2018 · https://doi.org/10.1038/s41580-018-0049-3

• Emerging paradigms in GPCR allostery: implications for drug discovery

  Nature Reviews Drug Discovery · 2013 · https://doi.org/10.1038/nrd4052

• Activation and allosteric modulation of a muscarinic acetylcholine receptor

  Nature · 2013 · https://doi.org/10.1038/nature12735

• Neuropsychopharmacology

  Journal · 2010 · https://doi.org/10.1007/978-3-540-68706-1_4410

• Allosteric Modulation of G Protein–Coupled Receptors

  The Annual Review of Pharmacology and Toxicology · 2006 · https://doi.org/10.1146/annurev.pharmtox.47.120505.105159

• Functional Selectivity and Classical Concepts of Quantitative Pharmacology

  Journal of Pharmacology and Experimental Therapeutics · 2006 · https://doi.org/10.1124/jpet.106.104463

• G-Protein–Coupled Receptor Mas Is a Physiological Antagonist of the Angiotensin II Type 1 Receptor

  Circulation · 2005 · https://doi.org/10.1161/01.cir.0000160867.23556.7d

Current projects

No projects listed.