François Bertucci

Research interests

Publications

• An integrated tumor, immune and microbiome atlas of colon cancer

  Nature Medicine · 2023 · https://doi.org/10.1038/s41591-023-02324-5

• Comprehensive metabolomics expands precision medicine for triple-negative breast cancer

  Cell Research · 2022 · https://doi.org/10.1038/s41422-022-00614-0

• Doxorubicin alone versus doxorubicin with trabectedin followed by trabectedin alone as first-line therapy for metastatic or unresectable leiomyosarcoma (LMS-04): a randomised, multicentre, open-label phase 3 trial

  The Lancet Oncology · 2022 · https://doi.org/10.1016/s1470-2045(22)00380-1

• Doxorubicin alone versus doxorubicin with trabectedin followed by trabectedin alone as first-line therapy for metastatic or unresectable leiomyosarcoma (LMS-04): a randomised, multicentre, open-label phase 3 trial

  The Lancet Oncology · 2022 · https://doi.org/10.1016/s1470-2045(22)00380-1

• Pazopanib or methotrexate–vinblastine combination chemotherapy in adult patients with progressive desmoid tumours (DESMOPAZ): a non-comparative, randomised, open-label, multicentre, phase 2 study

  The Lancet Oncology · 2019 · https://doi.org/10.1016/s1470-2045(19)30276-1

• Surgery in reference centers improves survival of sarcoma patients: a nationwide study

  Annals of Oncology · 2019 · https://doi.org/10.1093/annonc/mdz124

• Surgical versus non-surgical approach in primary desmoid-type fibromatosis patients: A nationwide prospective cohort from the French Sarcoma Group

  European Journal of Cancer · 2017 · https://doi.org/10.1016/j.ejca.2017.06.017

• Improved survival using specialized multidisciplinary board in sarcoma patients

  Annals of Oncology · 2017 · https://doi.org/10.1093/annonc/mdx484

• Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis

  OncoImmunology · 2017 · https://doi.org/10.1080/2162402x.2016.1253654

• Management of desmoid tumours: A nationwide survey of labelled reference centre networks in France

  European Journal of Cancer · 2016 · https://doi.org/10.1016/j.ejca.2016.02.008

• Safety and efficacy of regorafenib in patients with advanced soft tissue sarcoma (REGOSARC): a randomised, double-blind, placebo-controlled, phase 2 trial

  The Lancet Oncology · 2016 · https://doi.org/10.1016/s1470-2045(16)30507-1

• Genomic Characterization of Primary Invasive Lobular Breast Cancer

  Journal of Clinical Oncology · 2016 · https://doi.org/10.1200/jco.2015.64.0334

• Pazopanib plus best supportive care versus best supportive care alone in advanced gastrointestinal stromal tumours resistant to imatinib and sunitinib (PAZOGIST): a randomised, multicentre, open-label phase 2 trial

  The Lancet Oncology · 2016 · https://doi.org/10.1016/s1470-2045(16)00075-9

• Uncovering the Molecular Secrets of Inflammatory Breast Cancer Biology: An Integrated Analysis of Three Distinct Affymetrix Gene Expression Datasets

  Clinical Cancer Research · 2013 · https://doi.org/10.1158/1078-0432.ccr-12-2549

• CD47–signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction

  Proceedings of the National Academy of Sciences · 2011 · https://doi.org/10.1073/pnas.1106550108

• Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

  Journal of Clinical Investigation · 2011 · https://doi.org/10.1172/jci45816

• Neoadjuvant imatinib in patients with locally advanced non metastatic GIST in the prospective BFR14 trial

  BMC Cancer · 2011 · https://doi.org/10.1186/1471-2407-11-72

• Discontinuation of imatinib in patients with advanced gastrointestinal stromal tumours after 3 years of treatment: an open-label multicentre randomised phase 3 trial

  The Lancet Oncology · 2010 · https://doi.org/10.1016/s1470-2045(10)70222-9

• Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome

  Blood · 2008 · https://doi.org/10.1182/blood-2008-07-168096

Current projects

No projects listed.