Olivier Delattre

Research interests

Publications

• Ewing sarcoma

  Nature Reviews Disease Primers · 2018 · 10.1038/s41572-018-0003-x

• Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries

  Nature Genetics · 2017 · 10.1038/ng.3921

• Ewing Sarcoma: Current Management and Future Approaches Through Collaboration

  Journal of Clinical Oncology · 2015 · 10.1200/jco.2014.59.5256

• YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1

  The Journal of Cell Biology · 2015 · https://doi.org/10.1083/jcb.201411047

• Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis

  Cancer Cell · 2015 · https://doi.org/10.1016/j.ccell.2015.04.003

• Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3333

• Genomic Landscape of Ewing Sarcoma Defines an Aggressive Subtype with Co-Association of STAG2 and TP53 Mutations

  Cancer Discovery · 2014 · https://doi.org/10.1158/2159-8290.cd-14-0622

• Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

  Cancer Cell · 2014 · https://doi.org/10.1016/j.ccr.2014.02.004

• Cytogenetic Prognostication Within Medulloblastoma Subgroups

  Journal of Clinical Oncology · 2014 · https://doi.org/10.1200/jco.2013.50.9539

• Subgroup-specific structural variation across 1,000 medulloblastoma genomes

  Nature · 2012 · https://doi.org/10.1038/nature11327

• Systematic identification of genomic markers of drug sensitivity in cancer cells

  Nature · 2012 · https://doi.org/10.1038/nature11005

• Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with BRCA1/2 Inactivation

  Cancer Research · 2012 · https://doi.org/10.1158/0008-5472.can-12-1470

• Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

  Acta Neuropathologica · 2012 · https://doi.org/10.1007/s00401-012-0958-8

• A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion

  Nature Genetics · 2012 · 10.1038/ng.1107

• Control-FREEC: a tool for assessing copy number and allelic content using next-generation sequencing data

  Bioinformatics · 2011 · 10.1093/bioinformatics/btr670

• Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification

  Clinical Cancer Research · 2010 · https://doi.org/10.1158/1078-0432.ccr-09-2660

• Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome

  Journal of Clinical Oncology · 2010 · 10.1200/jco.2010.28.5148

• Fusion Gene–Negative Alveolar Rhabdomyosarcoma Is Clinically and Molecularly Indistinguishable From Embryonal Rhabdomyosarcoma

  Journal of Clinical Oncology · 2010 · 10.1200/jco.2009.26.3814

• Oxidative stress promotes myofibroblast differentiation and tumour spreading

  EMBO Molecular Medicine · 2010 · https://doi.org/10.1002/emmm.201000073

• MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma

  PLoS ONE · 2009 · https://doi.org/10.1371/journal.pone.0004998

• Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

  Nature · 2008 · 10.1038/nature07398

• A New Model of Patient Tumor-Derived Breast Cancer Xenografts for Preclinical Assays

  Clinical Cancer Research · 2007 · https://doi.org/10.1158/1078-0432.ccr-07-0078

• Mesenchymal Stem Cell Features of Ewing Tumors

  Cancer Cell · 2007 · 10.1016/j.ccr.2007.02.027

• Protein interaction mapping: ADrosophilacase study

  Genome Research · 2005 · 10.1101/gr.2659105

• Constitutional Mutations of the hSNF5/INI1 Gene Predispose to a Variety of Cancers

  The American Journal of Human Genetics · 1999 · 10.1086/302639

• Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

  Nature · 1998 · https://doi.org/10.1038/28212

• The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

  New England Journal of Medicine · 1994 · https://doi.org/10.1056/nejm199408043310503

• Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas

  Nature Genetics · 1994 · 10.1038/ng0294-180

• EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

  Nature Genetics · 1993 · 10.1038/ng0893-341

• Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

  Nature · 1993 · https://doi.org/10.1038/363515a0

• Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

  Proceedings of the National Academy of Sciences · 1993 · 10.1073/pnas.90.12.5752

• Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

  Nature · 1992 · https://doi.org/10.1038/359162a0

Current projects

No projects listed.