G Yeo

Research interests

Publications

• Emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States

  Cell · 2021 · https://doi.org/10.1016/j.cell.2021.03.052

• A large-scale binding and functional map of human RNA-binding proteins

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2077-3

• How RNA-Binding Proteins Interact with RNA: Molecules and Mechanisms

  Molecular Cell · 2020 · https://doi.org/10.1016/j.molcel.2020.03.011

• Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression

  Genome Medicine · 2020 · https://doi.org/10.1186/s13073-020-00812-8

• Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development

  Cell stem cell · 2019 · https://doi.org/10.1016/j.stem.2019.08.002

• Sequence, Structure, and Context Preferences of Human RNA Binding Proteins

  Molecular Cell · 2018 · https://doi.org/10.1016/j.molcel.2018.05.001

• Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules

  Cell · 2018 · https://doi.org/10.1016/j.cell.2017.12.032

• iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types

  Stem Cell Reports · 2017 · https://doi.org/10.1016/j.stemcr.2017.03.012

• Programmable RNA Tracking in Live Cells with CRISPR/Cas9

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.02.054

• Pairing beyond the Seed Supports MicroRNA Targeting Specificity

  Molecular Cell · 2016 · https://doi.org/10.1016/j.molcel.2016.09.004

• Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)

  Nature Methods · 2016 · https://doi.org/10.1038/nmeth.3810

• Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration

  Proceedings of the National Academy of Sciences · 2013 · https://doi.org/10.1073/pnas.1318835110

• ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43

  Proceedings of the National Academy of Sciences · 2013 · https://doi.org/10.1073/pnas.1222809110

• Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

  Nature Neuroscience · 2012 · https://doi.org/10.1038/nn.3230

• Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43

  Nature Neuroscience · 2011 · https://doi.org/10.1038/nn.2779

• A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

  Cell · 2010 · https://doi.org/10.1016/j.cell.2010.10.016

• L1 retrotransposition in neurons is modulated by MeCP2

  Nature · 2010 · https://doi.org/10.1038/nature09544

• Genome-wide Analysis of PTB-RNA Interactions Reveals a Strategy Used by the General Splicing Repressor to Modulate Exon Inclusion or Skipping

  Molecular Cell · 2009 · https://doi.org/10.1016/j.molcel.2009.12.003

• L1 retrotransposition in human neural progenitor cells

  Nature · 2009 · https://doi.org/10.1038/nature08248

• Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis

  Nature Neuroscience · 2009 · https://doi.org/10.1038/nn.2360

• An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells

  Nature Structural & Molecular Biology · 2009 · https://doi.org/10.1038/nsmb.1545

• Divergent Transcription from Active Promoters

  Science · 2008 · https://doi.org/10.1126/science.1162253

• Variation in alternative splicing across human tissues

  Genome biology · 2004 · https://doi.org/10.1186/gb-2004-5-10-r74

• Systematic Identification and Analysis of Exonic Splicing Silencers

  Cell · 2004 · https://doi.org/10.1016/j.cell.2004.11.010

• Maximum Entropy Modeling of Short Sequence Motifs with Applications to RNA Splicing Signals

  Journal of Computational Biology · 2004 · https://doi.org/10.1089/1066527041410418

Current projects

No projects listed.