Daniel Birnbaum

Research interests

Publications

• Genomic characterization of metastatic breast cancers

  Nature · 2019 · 10.1038/s41586-019-1056-z

• Salinomycin kills cancer stem cells by sequestering iron in lysosomes

  Nature Chemistry · 2017 · 10.1038/nchem.2778

• Improving genetic diagnosis in Mendelian disease with transcriptome sequencing

  Science Translational Medicine · 2017 · 10.1126/scitranslmed.aal5209

• The ExAC browser: displaying reference data information from over 60 000 exomes

  Nucleic Acids Research · 2016 · 10.1093/nar/gkw971

• A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms12222

• Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States Reflective of their Normal Counterparts

  Stem Cell Reports · 2014 · 10.1016/j.stemcr.2013.11.009

• Prognostic and predictive value of PDL1 expression in breast cancer

  Oncotarget · 2014 · 10.18632/oncotarget.3216

• Uncovering the Molecular Secrets of Inflammatory Breast Cancer Biology: An Integrated Analysis of Three Distinct Affymetrix Gene Expression Datasets

  Clinical Cancer Research · 2013 · https://doi.org/10.1158/1078-0432.ccr-12-2549

• Prognostic Score Including Gene Mutations in Chronic Myelomonocytic Leukemia

  Journal of Clinical Oncology · 2013 · 10.1200/jco.2012.47.3314

• BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders

  Blood · 2013 · https://doi.org/10.1182/blood-2012-11-469619

• Basal Breast Cancer: A Complex and Deadly Molecular Subtype

  Current Molecular Medicine · 2011 · 10.2174/156652412798376134

• Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

  Journal of Clinical Investigation · 2011 · https://doi.org/10.1172/jci45816

• CD47–signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction

  Proceedings of the National Academy of Sciences · 2011 · https://doi.org/10.1073/pnas.1106550108

• CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts

  Journal of Clinical Investigation · 2010 · 10.1172/jci39397

• Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature

  Cancer Research · 2009 · 10.1158/0008-5472.can-08-2741

• Mutations of polycomb‐associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia

  British Journal of Haematology · 2009 · 10.1111/j.1365-2141.2009.07697.x

• Aldehyde Dehydrogenase 1–Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer

  Clinical Cancer Research · 2009 · 10.1158/1078-0432.ccr-09-1630

• Mutations of ASXL1 gene in myeloproliferative neoplasms

  Leukemia · 2009 · 10.1038/leu.2009.141

• Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome

  Blood · 2008 · https://doi.org/10.1182/blood-2008-07-168096

• How basal are triple‐negative breast cancers?

  International Journal of Cancer · 2008 · 10.1002/ijc.23518

• ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome

  Cell stem cell · 2007 · 10.1016/j.stem.2007.08.014

• Gene Expression Profiling Shows Medullary Breast Cancer Is a Subgroup of Basal Breast Cancers

  Cancer Research · 2006 · 10.1158/0008-5472.can-06-0031

• Gene expression profiling of breast cell lines identifies potential new basal markers

  Oncogene · 2005 · 10.1038/sj.onc.1209254

• Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters

  Oncogene · 2004 · 10.1038/sj.onc.1207262

• ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor

  Nature Cell Biology · 2000 · 10.1038/35017038

• Spectrum of hSNF5IINI1 Somatic Mutations in Human Cancer and Genotype-Phenotype Correlations

  Human Molecular Genetics · 1999 · 10.1093/hmg/8.13.2359

• Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs

  Nature · 1994 · 10.1038/368643a0

• Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells

  Blood · 1993 · 10.1182/blood.v82.4.1110.1110

• Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.

  PubMed · 1991

• Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1

  Nature · 1983 · 10.1038/304497a0

Current projects

No projects listed.