Jean Bourhis

Research interests

Publications

• Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group

  Radiotherapy and Oncology · 2021 · https://doi.org/10.1016/j.radonc.2021.01.013

• Avelumab plus standard-of-care chemoradiotherapy versus chemoradiotherapy alone in patients with locally advanced squamous cell carcinoma of the head and neck: a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial

  The Lancet Oncology · 2021 · https://doi.org/10.1016/s1470-2045(20)30737-3

• Treatment of a first patient with FLASH-radiotherapy

  Radiotherapy and Oncology · 2019 · https://doi.org/10.1016/j.radonc.2019.06.019

• Long-term neurocognitive benefits of FLASH radiotherapy driven by reduced reactive oxygen species

  Proceedings of the National Academy of Sciences · 2019 · https://doi.org/10.1073/pnas.1901777116

• The Advantage of FLASH Radiotherapy Confirmed in Mini-pig and Cat-cancer Patients

  Clinical Cancer Research · 2018 · https://doi.org/10.1158/1078-0432.ccr-17-3375

• Role of radiotherapy fractionation in head and neck cancers (MARCH): an updated meta-analysis

  The Lancet Oncology · 2017 · https://doi.org/10.1016/s1470-2045(17)30458-8

• Delineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma: AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines

  Radiotherapy and Oncology · 2017 · https://doi.org/10.1016/j.radonc.2017.10.016

• Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100 Gy/s

  Radiotherapy and Oncology · 2017 · https://doi.org/10.1016/j.radonc.2017.05.003

• Role of radiotherapy fractionation in head and neck cancers (MARCH): an updated meta-analysis

  The Lancet Oncology · 2017 · https://doi.org/10.1016/s1470-2045(17)30458-8

• Role of radiotherapy fractionation in head and neck cancers (MARCH): an updated meta-analysis

  The Lancet Oncology · 2017 · https://doi.org/10.1016/s1470-2045(17)30458-8

• Radiotherapy combination opportunities leveraging immunity for the next oncology practice

  CA A Cancer Journal for Clinicians · 2016 · https://doi.org/10.3322/caac.21358

• Chemotherapy and radiotherapy in nasopharyngeal carcinoma: an update of the MAC-NPC meta-analysis

  The Lancet Oncology · 2015 · https://doi.org/10.1016/s1470-2045(15)70126-9

• Role of allogeneic stem cell transplantation in adult patients with Ph-negative acute lymphoblastic leukemia

  Blood · 2015 · https://doi.org/10.1182/blood-2014-09-599894

• CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines

  Radiotherapy and Oncology · 2015 · https://doi.org/10.1016/j.radonc.2015.07.041

• Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice

  Science Translational Medicine · 2014 · https://doi.org/10.1126/scitranslmed.3008973

• A phase 1 trial of the anti-inhibitory KIR mAb IPH2101 for AML in complete remission

  Blood · 2012 · https://doi.org/10.1182/blood-2012-06-437558

• Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): A comprehensive analysis by tumour site

  Radiotherapy and Oncology · 2011 · https://doi.org/10.1016/j.radonc.2011.05.036

• Critical Impact of Radiotherapy Protocol Compliance and Quality in the Treatment of Advanced Head and Neck Cancer: Results From TROG 02.02

  Journal of Clinical Oncology · 2010 · https://doi.org/10.1200/jco.2009.27.4498

• Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients

  Radiotherapy and Oncology · 2009 · https://doi.org/10.1016/j.radonc.2009.04.014

• Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

  Nature Medicine · 2007 · https://doi.org/10.1038/nm1622

• Maintenance therapy with thalidomide improves survival in patients with multiple myeloma

  Blood · 2006 · https://doi.org/10.1182/blood-2006-05-022962

• Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis

  The Lancet · 2006 · https://doi.org/10.1016/s0140-6736(06)69121-6

• Phase II Multicenter Study of the Antiepidermal Growth Factor Receptor Monoclonal Antibody Cetuximab in Combination With Platinum-Based Chemotherapy in Patients With Platinum-Refractory Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck

  Journal of Clinical Oncology · 2005 · https://doi.org/10.1200/jco.2005.07.119

• Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)

  Head & Neck · 2005 · https://doi.org/10.1002/hed.20279

• Chemotherapy in locally advanced nasopharyngeal carcinoma: An individual patient data meta-analysis of eight randomized trials and 1753 patients

  International Journal of Radiation Oncology*Biology*Physics · 2005 · https://doi.org/10.1016/j.ijrobp.2005.06.037

• Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck Cancer

  New England Journal of Medicine · 2004 · https://doi.org/10.1056/nejmoa032641

• Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta analysis of chemotherapy on head and neck cancer

  Cancer/Radiothérapie · 2001 · https://doi.org/10.1016/s1278-3218(00)00073-1

• Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data

  The Lancet · 2000 · https://doi.org/10.1016/s0140-6736(00)90011-4

Current projects

No projects listed.