Éric Bouffet

Research interests

Publications

• Sustainable care for children with cancer: a Lancet Oncology Commission

  The Lancet Oncology · 2020 · 10.1016/s1470-2045(20)30022-x

• Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas

  Cancer Cell · 2020 · https://doi.org/10.1016/j.ccell.2020.03.011

• Science and health for all children with cancer

  Science · 2019 · 10.1126/science.aaw4892

• Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas

  Nature Communications · 2019 · 10.1038/s41467-019-12187-5

• Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries

  Journal of Clinical Oncology · 2018 · https://doi.org/10.1200/jco.2017.75.9308

• Comprehensive Analysis of Hypermutation in Human Cancer

  Cell · 2017 · https://doi.org/10.1016/j.cell.2017.09.048

• Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas

  Journal of Clinical Oncology · 2017 · https://doi.org/10.1200/jco.2016.71.8726

• Intertumoral Heterogeneity within Medulloblastoma Subgroups

  Cancer Cell · 2017 · https://doi.org/10.1016/j.ccell.2017.05.005

• The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants

  Acta Neuropathologica · 2016 · 10.1007/s00401-016-1643-0

• Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency

  Journal of Clinical Oncology · 2016 · https://doi.org/10.1200/jco.2016.66.6552

• Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis

  The Lancet Oncology · 2016 · https://doi.org/10.1016/s1470-2045(15)00581-1

• Risk stratification of childhood medulloblastoma in the molecular era: the current consensus

  Acta Neuropathologica · 2016 · https://doi.org/10.1007/s00401-016-1569-6

• Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3202

• MRI Surrogates for Molecular Subgroups of Medulloblastoma

  American Journal of Neuroradiology · 2014 · 10.3174/ajnr.a3990

• Cytogenetic Prognostication Within Medulloblastoma Subgroups

  Journal of Clinical Oncology · 2014 · https://doi.org/10.1200/jco.2013.50.9539

• Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

  Nature · 2014 · https://doi.org/10.1038/nature13108

• Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.2936

• Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications

  Acta Neuropathologica · 2014 · 10.1007/s00401-014-1319-6

• Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis

  The Lancet Oncology · 2013 · https://doi.org/10.1016/s1470-2045(13)70449-2

• Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma

  Journal of Clinical Oncology · 2013 · https://doi.org/10.1200/jco.2012.48.5052

• Novel mutations target distinct subgroups of medulloblastoma

  Nature · 2012 · https://doi.org/10.1038/nature11213

• Clonal selection drives genetic divergence of metastatic medulloblastoma

  Nature · 2012 · https://doi.org/10.1038/nature10825

• K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

  Acta Neuropathologica · 2012 · https://doi.org/10.1007/s00401-012-0998-0

• Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples

  Acta Neuropathologica · 2011 · https://doi.org/10.1007/s00401-011-0899-7

• Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: a report from the Children's Oncology Group

  Neuro-Oncology · 2011 · 10.1093/neuonc/noq205

• Medulloblastoma Comprises Four Distinct Molecular Variants

  Journal of Clinical Oncology · 2010 · https://doi.org/10.1200/jco.2009.27.4324

• Diffuse brainstem glioma in children: critical review of clinical trials

  The Lancet Oncology · 2006 · 10.1016/s1470-2045(06)70615-5

• Change in Neurocognitive Functioning After Treatment With Cranial Radiation in Childhood

  Journal of Clinical Oncology · 2004 · 10.1200/jco.2004.05.186

Current projects

No projects listed.