Graham Pawelec

Research interests

Publications

• Immunology of Aging: the Birth of Inflammaging

  Clinical Reviews in Allergy & Immunology · 2021 · 10.1007/s12016-021-08899-6

• Relationships Between Immune Landscapes, Genetic Subtypes and Responses to Immunotherapy in Colorectal Cancer

  Frontiers in Immunology · 2020 · 10.3389/fimmu.2020.00369

• Aging in COVID-19: Vulnerability, immunity and intervention

  Ageing Research Reviews · 2020 · https://doi.org/10.1016/j.arr.2020.101205

• The Immune System and Its Dysregulation with Aging

  Sub-cellular biochemistry/Subcellular biochemistry · 2019 · https://doi.org/10.1007/978-981-13-3681-2_2

• Age and immunity: What is “immunosenescence”?

  Experimental Gerontology · 2017 · 10.1016/j.exger.2017.10.024

• Baseline Peripheral Blood Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab

  Clinical Cancer Research · 2016 · 10.1158/1078-0432.ccr-15-2412

• Immune evasion in cancer: Mechanistic basis and therapeutic strategies

  Seminars in Cancer Biology · 2015 · https://doi.org/10.1016/j.semcancer.2015.03.004

• Inflammation, ageing and chronic disease

  Current Opinion in Immunology · 2014 · 10.1016/j.coi.2014.03.007

• A Consideration of Biomarkers to be Used for Evaluation of Inflammation in Human Nutritional Studies

  British Journal Of Nutrition · 2013 · 10.1017/s0007114512005119

• Cancer classification using the Immunoscore: a worldwide task force

  Journal of Translational Medicine · 2012 · https://doi.org/10.1186/1479-5876-10-205

• Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival

  Nature Medicine · 2012 · https://doi.org/10.1038/nm.2883

• Seropositivity to Cytomegalovirus, Inflammation, All-Cause and Cardiovascular Disease-Related Mortality in the United States

  PLoS ONE · 2011 · https://doi.org/10.1371/journal.pone.0016103

• Aging, frailty and age-related diseases

  Biogerontology · 2010 · https://doi.org/10.1007/s10522-010-9287-2

• Epigenetic and immune function profiles associated with posttraumatic stress disorder

  Proceedings of the National Academy of Sciences · 2010 · 10.1073/pnas.0910794107

• Direct Injection of Protamine-protected mRNA: Results of a Phase 1/2 Vaccination Trial in Metastatic Melanoma Patients

  Journal of Immunotherapy · 2009 · https://doi.org/10.1097/cji.0b013e3181a00068

• Aging of the Immune System as a Prognostic Factor for Human Longevity

  Physiology · 2008 · https://doi.org/10.1152/physiol.00040.2007

• Cytomegalovirus and human immunosenescence

  Reviews in Medical Virology · 2008 · https://doi.org/10.1002/rmv.598

• Multiparameter flow cytometric analysis of CD4 and CD8 T cell subsets in young and old people

  Immunity & Ageing · 2008 · https://doi.org/10.1186/1742-4933-5-6

• Longitudinal Studies of Clonally Expanded CD8 T Cells Reveal a Repertoire Shrinkage Predicting Mortality and an Increased Number of Dysfunctional Cytomegalovirus-Specific T Cells in the Very Elderly

  The Journal of Immunology · 2006 · 10.4049/jimmunol.176.4.2645

• Aging and Innate Immunity

  Immunity · 2006 · https://doi.org/10.1016/j.immuni.2006.05.003

• An Immune Risk Phenotype, Cognitive Impairment, and Survival in Very Late Life: Impact of Allostatic Load in Swedish Octogenarian and Nonagenarian Humans

  The Journals of Gerontology Series A · 2005 · 10.1093/gerona/60.5.556

• Human immunosenescence: is it infectious?

  Immunological Reviews · 2005 · 10.1111/j.0105-2896.2005.00271.x

• Extrathymic T-cell differentiation in vitro

  Nature reviews. Immunology · 2004 · https://doi.org/10.1038/nri1257-c1

• T cells and aging january 2002 update

  Frontiers in bioscience · 2002 · https://doi.org/10.2741/a831

• T cells and aging

  Frontiers in bioscience · 1998 · https://doi.org/10.2741/a266

Current projects

No projects listed.