James T. Rutka

Research interests

Publications

• Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas

  Cancer Cell · 2020 · https://doi.org/10.1016/j.ccell.2020.03.011

• Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas

  Journal of Clinical Oncology · 2017 · https://doi.org/10.1200/jco.2016.71.8726

• Intertumoral Heterogeneity within Medulloblastoma Subgroups

  Cancer Cell · 2017 · https://doi.org/10.1016/j.ccell.2017.05.005

• Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

  Nature · 2017 · https://doi.org/10.1038/nature25169

• BRAF Mutation and CDKN2A Deletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma

  Journal of Clinical Oncology · 2015 · https://doi.org/10.1200/jco.2014.58.3922

• Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis

  The Lancet Oncology · 2015 · https://doi.org/10.1016/s1470-2045(15)70114-2

• Study of the biodistribution of fluorescein in glioma-infiltrated mouse brain and histopathological correlation of intraoperative findings in high-grade gliomas resected under fluorescein fluorescence guidance

  Journal of neurosurgery · 2015 · https://doi.org/10.3171/2015.2.jns132507

• Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

  Nature · 2014 · https://doi.org/10.1038/nature13108

• Cytogenetic Prognostication Within Medulloblastoma Subgroups

  Journal of Clinical Oncology · 2014 · https://doi.org/10.1200/jco.2013.50.9539

• Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis

  The Lancet Oncology · 2013 · https://doi.org/10.1016/s1470-2045(13)70449-2

• TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma

  Acta Neuropathologica · 2013 · https://doi.org/10.1007/s00401-013-1198-2

• Glioblastoma, a Brief Review of History, Molecular Genetics, Animal Models and Novel Therapeutic Strategies

  Archivum Immunologiae et Therapiae Experimentalis · 2012 · https://doi.org/10.1007/s00005-012-0203-0

• Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples

  Acta Neuropathologica · 2011 · https://doi.org/10.1007/s00401-011-0899-7

• Medulloblastoma Comprises Four Distinct Molecular Variants

  Journal of Clinical Oncology · 2010 · https://doi.org/10.1200/jco.2009.27.4324

• Change in Neurocognitive Functioning After Treatment With Cranial Radiation in Childhood

  Journal of Clinical Oncology · 2004 · https://doi.org/10.1200/jco.2004.05.186

Current projects

No projects listed.