George Klein

Research interests

Publications

• The candidate tumor suppressor gene, RASSF1A , from human chromosome 3p21.3 is involved in kidney tumorigenesis

  Proceedings of the National Academy of Sciences · 2001 · https://doi.org/10.1073/pnas.131216298

• Inhibition of antigen processing by the internal repeat region of the Epstein–Barr virus nuclear antigen-1

  Nature · 1995 · https://doi.org/10.1038/375685a0

• Morphological transformation of human keratinocytes expressing the LMP gene of Epstein Barr virus

  Nature · 1990 · https://doi.org/10.1038/345447a0

• The Approaching Era of the Tumor Suppressor Genes

  Science · 1987 · https://doi.org/10.1126/science.3317834

• Evolution of tumours and the impact of molecular oncology

  Nature · 1985 · https://doi.org/10.1038/315190a0

• Specific chromosomal translocations and the genesis of B-cell-derived tumors in mice and men

  Cell · 1983 · https://doi.org/10.1016/0092-8674(83)90449-x

• The role of gene dosage and genetic transpositions in carcinogenesis

  Nature · 1981 · https://doi.org/10.1038/294313a0

• Induction of the Epstein-Barr virus (EBV) cycle in latently infected cells by n-butyrate

  Virology · 1979 · https://doi.org/10.1016/0042-6822(79)90455-0

• Lymphoma development in mice and humans: diversity of initiation is followed by convergent cytogenetic evolution.

  Proceedings of the National Academy of Sciences · 1979 · https://doi.org/10.1073/pnas.76.5.2442

• Polyclonal Ig production after Epstein-Barr virus infection of human lymphocytes in vitro

  Nature · 1977 · https://doi.org/10.1038/267052a0

• EB virus-induced B lymphocyte cell lines producing specific antibody

  Nature · 1977 · https://doi.org/10.1038/269420a0

• Characteristic chromosomal abnormalities in biopsies and lymphoid‐cell lines from patients with burkitt and non‐burkitt lymphomas

  International Journal of Cancer · 1976 · https://doi.org/10.1002/ijc.2910170108

• An EBV-Genome-Negative Cell Line Established from an American Burkitt Lymphoma; Receptor Characteristics. EBV Infectibility and Permanent Conversion into EBV-Positive Sublines by in vitro Infection

  Intervirology · 1975 · https://doi.org/10.1159/000149930

• Establishment and characterization of an Epstein-Barr virus (EBC)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome-negative African Burkitt's lymphoma.

  PubMed · 1975

• Direct Evidence for the Presence of Epstein-Barr Virus DNA and Nuclear Antigen in Malignant Epithelial Cells from Patients with Poorly Differentiated Carcinoma of the Nasopharynx

  Proceedings of the National Academy of Sciences · 1974 · https://doi.org/10.1073/pnas.71.12.4737

• Relationship between Epstein‐Barr virus (EBV) DNA and the EBV‐determined nuclear antigen (EBNA) in Burkitt lymphoma biopsies and other lymphoproliferative malignancies

  International Journal of Cancer · 1974 · https://doi.org/10.1002/ijc.2910130605

• Continuous Lymphoid Cell Lines with Characteristics of B Cells (Bone-Marrow-Derived), Lacking the Epstein-Barr Virus Genome and Derived from Three Human Lymphomas

  Proceedings of the National Academy of Sciences · 1974 · https://doi.org/10.1073/pnas.71.8.3283

• SURFACE MARKERS ON HUMAN B AND T LYMPHOCYTES

  The Journal of Experimental Medicine · 1973 · https://doi.org/10.1084/jem.138.6.1365

• Cellular localization of an Epstein‐Barr virus (EBV)‐associated complement‐fixing antigen in producer and non‐producer lymphoblastoid cell lines

  International Journal of Cancer · 1973 · https://doi.org/10.1002/ijc.2910110302

• Sensitivity of Epstein‐Barr virus (EBV) producer and non‐producer human lymphoblastoid cell lines to superinfection with EB‐virus

  International Journal of Cancer · 1972 · https://doi.org/10.1002/ijc.2910100108

• The establishment of lymphoblastoid lines from adult and fetal human lymphoid tissue and its dependence on EBV

  International Journal of Cancer · 1971 · https://doi.org/10.1002/ijc.2910080312

• Antibodies to Epstein-Barr Virus in Burkitt's Lymphoma and Control Groups 2

  JNCI Journal of the National Cancer Institute · 1969 · https://doi.org/10.1093/jnci/43.5.1147

• Suppression of Malignancy by Cell Fusion

  Nature · 1969 · https://doi.org/10.1038/223363a0

• Tumor Antigens

  Annual Review of Microbiology · 1966 · https://doi.org/10.1146/annurev.mi.20.100166.001255

• Antigenic Properties of Lymphomas Induced by the Moloney Agent 2

  JNCI Journal of the National Cancer Institute · 1964 · https://doi.org/10.1093/jnci/32.3.547

• Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host.

  PubMed · 1960

Current projects

No projects listed.