Yunlong Liu

Research interests

Publications

• Refining colorectal cancer classification and clinical stratification through a single-cell atlas

  Genome biology · 2022 · https://doi.org/10.1186/s13059-022-02677-z

• Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-021-21823-y

• Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia

  The Journal of Experimental Medicine · 2021 · https://doi.org/10.1084/jem.20190450

• Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

  Nature Neuroscience · 2021 · https://doi.org/10.1038/s41593-021-00908-3

• Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment

  Alzheimer s Research & Therapy · 2021 · https://doi.org/10.1186/s13195-021-00850-3

• The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline

  eLife · 2021 · https://doi.org/10.7554/elife.62270

• Atractylenolide I enhances responsiveness to immune checkpoint blockade therapy by activating tumor antigen presentation

  Journal of Clinical Investigation · 2021 · https://doi.org/10.1172/jci146832

• CNS-Native Myeloid Cells Drive Immune Suppression in the Brain Metastatic Niche through Cxcl10

  Cell · 2020 · https://doi.org/10.1016/j.cell.2020.09.064

• MAL2 drives immune evasion in breast cancer by suppressing tumor antigen presentation

  Journal of Clinical Investigation · 2020 · https://doi.org/10.1172/jci140837

• Hair-bearing human skin generated entirely from pluripotent stem cells

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2352-3

• Comprehensive comparison of molecular portraits between cell lines and tumors in breast cancer

  BMC Genomics · 2016 · https://doi.org/10.1186/s12864-016-2911-z

• Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs

  Oncotarget · 2016 · https://doi.org/10.18632/oncotarget.9779

• The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

  Cancer Cell · 2015 · https://doi.org/10.1016/j.ccell.2015.04.009

• Epigenetic Targeting of Ovarian Cancer Stem Cells

  Cancer Research · 2014 · https://doi.org/10.1158/0008-5472.can-14-1022

• TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells

  Epigenetics · 2014 · https://doi.org/10.4161/15592294.2014.971608

• Hepatic FoxOs Regulate Lipid Metabolism via Modulation of Expression of the Nicotinamide Phosphoribosyltransferase Gene

  Journal of Biological Chemistry · 2011 · https://doi.org/10.1074/jbc.m110.201061

• MicroRNA Cluster 221-222 and Estrogen Receptor α Interactions in Breast Cancer

  JNCI Journal of the National Cancer Institute · 2010 · https://doi.org/10.1093/jnci/djq102

• Gene expression patterns in bone following mechanical loading

  Journal of Bone and Mineral Research · 2010 · https://doi.org/10.1002/jbmr.193

• Prioritization of disease microRNAs through a human phenome-microRNAome network

  BMC Systems Biology · 2010 · https://doi.org/10.1186/1752-0509-4-s1-s2

• Predicting intrinsic disorder in proteins: an overview

  Cell Research · 2009 · https://doi.org/10.1038/cr.2009.87

• Estradiol-regulated microRNAs control estradiol response in breast cancer cells

  Nucleic Acids Research · 2009 · https://doi.org/10.1093/nar/gkp500

• Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation

  Epigenetics · 2009 · https://doi.org/10.4161/epi.4.7.9925

• Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts

  Genome Research · 2008 · https://doi.org/10.1101/gr.082503.108

Current projects

No projects listed.