Nathalie Vergnolle

Research interests

Publications

• Guidance on the planning and reporting of experimental design and analysis

  British Journal of Pharmacology · 2025 · 10.1111/bph.17441

• Planning experiments: Updated guidance on experimental design and analysis and their reporting III

  British Journal of Pharmacology · 2022 · https://doi.org/10.1111/bph.15868

• Gastrointestinal biofilms in health and disease

  Nature Reviews Gastroenterology & Hepatology · 2021 · 10.1038/s41575-020-00397-y

• Protease inhibition as new therapeutic strategy for GI diseases

  Gut · 2016 · 10.1136/gutjnl-2015-309147

• The Intestinal Microenvironment and Functional Gastrointestinal Disorders

  Gastroenterology · 2016 · 10.1053/j.gastro.2016.02.028

• LC–MS/MS method for rapid and concomitant quantification of pro-inflammatory and pro-resolving polyunsaturated fatty acid metabolites

  Journal of Chromatography B · 2013 · 10.1016/j.jchromb.2013.06.014

• TRPM8 activation attenuates inflammatory responses in mouse models of colitis

  Proceedings of the National Academy of Sciences · 2013 · https://doi.org/10.1073/pnas.1217431110

• Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis

  Science Translational Medicine · 2012 · 10.1126/scitranslmed.3004212

• Potentiation of TRPV4 signalling by histamine and serotonin: an important mechanism for visceral hypersensitivity

  Gut · 2010 · 10.1136/gut.2009.192567

• Transient Receptor Potential Vanilloid-4 Has a Major Role in Visceral Hypersensitivity Symptoms

  Gastroenterology · 2008 · https://doi.org/10.1053/j.gastro.2008.05.024

• Role for protease activity in visceral pain in irritable bowel syndrome

  Journal of Clinical Investigation · 2007 · https://doi.org/10.1172/jci29255

• Protease‐activated receptor 2 sensitizes TRPV1 by protein kinase Cɛ‐ and A‐dependent mechanisms in rats and mice

  The Journal of Physiology · 2006 · 10.1113/jphysiol.2006.111534

• Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice

  The Journal of Physiology · 2006 · 10.1113/jphysiol.2006.121111

• A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis

  Proceedings of the National Academy of Sciences · 2005 · https://doi.org/10.1073/pnas.0409535102

• Protease-Activated Receptor 2 Sensitizes the Capsaicin Receptor Transient Receptor Potential Vanilloid Receptor 1 to Induce Hyperalgesia

  Journal of Neuroscience · 2004 · 10.1523/jneurosci.5679-03.2004

• Proteinase-Activated Receptors: Transducers of Proteinase-Mediated Signaling in Inflammation and Immune Response

  Endocrine Reviews · 2004 · https://doi.org/10.1210/er.2003-0025

• Induction of Intestinal Inflammation in Mouse by Activation of Proteinase-Activated Receptor-2

  American Journal Of Pathology · 2002 · 10.1016/s0002-9440(10)64466-5

• Proteinases and proteinase-activated receptor 2: A possible role to promote visceral hyperalgesia in rats

  Gastroenterology · 2002 · 10.1053/gast.2002.32387

• Protease-activated receptors in inflammation, neuronal signaling and pain

  Trends in Pharmacological Sciences · 2001 · 10.1016/s0165-6147(00)01634-5

• Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway

  Nature Medicine · 2001 · 10.1038/89945

• Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis

  Proceedings of the National Academy of Sciences · 2001 · 10.1073/pnas.241377298

• NSAID-induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2

  Gastroenterology · 2000 · https://doi.org/10.1053/gast.2000.16510

• Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

  Nature Medicine · 2000 · https://doi.org/10.1038/72247

• Characterization of the inflammatory response to proteinase‐activated receptor‐2 (PAR2)‐activating peptides in the rat paw

  British Journal of Pharmacology · 1999 · 10.1038/sj.bjp.0702634

• Proteinase-Activated Receptor-2-Activating Peptides Induce Leukocyte Rolling, Adhesion, and Extravasation In Vivo

  The Journal of Immunology · 1999 · 10.4049/jimmunol.163.9.5064

Current projects

No projects listed.