Nada Jabado

Research interests

Publications

• Childhood cerebellar tumours mirror conserved fetal transcriptional programs

  Nature · 2019 · https://doi.org/10.1038/s41586-019-1158-7

• Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort

  The Lancet Oncology · 2018 · https://doi.org/10.1016/s1470-2045(18)30242-0

• Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

  Cancer Cell · 2017 · https://doi.org/10.1016/j.ccell.2017.08.017

• Intertumoral Heterogeneity within Medulloblastoma Subgroups

  Cancer Cell · 2017 · https://doi.org/10.1016/j.ccell.2017.05.005

• The whole-genome landscape of medulloblastoma subtypes

  Nature · 2017 · https://doi.org/10.1038/nature22973

• Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas

  Journal of Clinical Oncology · 2017 · https://doi.org/10.1200/jco.2016.71.8726

• Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis

  The Lancet Oncology · 2016 · https://doi.org/10.1016/s1470-2045(15)00581-1

• Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency

  Journal of Clinical Oncology · 2016 · https://doi.org/10.1200/jco.2016.66.6552

• Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes

  Cancer Cell · 2016 · https://doi.org/10.1016/j.ccell.2016.02.001

• Utility of whole‐exome sequencing for those near the end of the diagnostic odyssey: time to address gaps in care

  Clinical Genetics · 2015 · https://doi.org/10.1111/cge.12654

• Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

  Nature · 2014 · https://doi.org/10.1038/nature13108

• Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

  Cancer Cell · 2014 · https://doi.org/10.1016/j.ccr.2014.02.004

• Cytogenetic Prognostication Within Medulloblastoma Subgroups

  Journal of Clinical Oncology · 2014 · https://doi.org/10.1200/jco.2013.50.9539

• Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

  Cancer Cell · 2013 · 10.1016/j.ccr.2013.10.006

• Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis

  The Lancet Oncology · 2013 · https://doi.org/10.1016/s1470-2045(13)70449-2

• Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas

  Acta Neuropathologica · 2013 · https://doi.org/10.1007/s00401-013-1095-8

• Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma

  Journal of Clinical Oncology · 2013 · https://doi.org/10.1200/jco.2012.48.5052

• Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2682

• Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

  Cell · 2012 · https://doi.org/10.1016/j.cell.2011.12.013

• Subgroup-specific structural variation across 1,000 medulloblastoma genomes

  Nature · 2012 · https://doi.org/10.1038/nature11327

• Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

  Cancer Cell · 2012 · https://doi.org/10.1016/j.ccr.2012.08.024

• Dissecting the genomic complexity underlying medulloblastoma

  Nature · 2012 · https://doi.org/10.1038/nature11284

• Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations

  Acta Neuropathologica · 2012 · https://doi.org/10.1007/s00401-012-1031-3

• K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

  Acta Neuropathologica · 2012 · https://doi.org/10.1007/s00401-012-0998-0

• Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

  Nature · 2012 · https://doi.org/10.1038/nature10833

Current projects

No projects listed.