Mark A. Jenkins

Research interests

Publications

• Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

  Nature Genetics · 2022 · https://doi.org/10.1038/s41588-022-01222-9

• Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk

  The American Journal of Human Genetics · 2020 · https://doi.org/10.1016/j.ajhg.2020.07.006

• Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

  BMC Medicine · 2020 · https://doi.org/10.1186/s12916-020-01855-9

• Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-020-14389-8

• Association analyses identify 31 new risk loci for colorectal cancer susceptibility

  Nature Communications · 2019 · https://doi.org/10.1038/s41467-019-09775-w

• Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses

  Gastroenterology · 2019 · https://doi.org/10.1053/j.gastro.2019.12.020

• Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

  Genetics in Medicine · 2019 · https://doi.org/10.1038/s41436-019-0596-9

• Novel Common Genetic Susceptibility Loci for Colorectal Cancer

  JNCI Journal of the National Cancer Institute · 2018 · https://doi.org/10.1093/jnci/djy099

• Global trends in colorectal cancer mortality: projections to the year 2035

  International Journal of Cancer · 2018 · https://doi.org/10.1002/ijc.32055

• Discovery of common and rare genetic risk variants for colorectal cancer

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0286-6

• Cancer Risks for PMS2 -Associated Lynch Syndrome

  Journal of Clinical Oncology · 2018 · https://doi.org/10.1200/jco.2018.78.4777

• Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database

  Gut · 2017 · https://doi.org/10.1136/gutjnl-2017-314057

• Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

  Cancer Research · 2016 · https://doi.org/10.1158/0008-5472.can-15-2980

• Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent

  PLoS Medicine · 2016 · https://doi.org/10.1371/journal.pmed.1002105

• Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer

  Cancer Epidemiology Biomarkers & Prevention · 2016 · https://doi.org/10.1158/1055-9965.epi-16-0693

• Identification of Lynch Syndrome Among Patients With Colorectal Cancer

  JAMA · 2012 · https://doi.org/10.1001/jama.2012.13088

• Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

  Gastroenterology · 2012 · https://doi.org/10.1053/j.gastro.2012.12.020

• Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer

  PLoS Genetics · 2011 · https://doi.org/10.1371/journal.pgen.1002105

• A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

  Nature · 2011 · https://doi.org/10.1038/nature10630

• Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

  The Lancet · 2011 · https://doi.org/10.1016/s0140-6736(11)60874-x

• Genome-wide association study identifies three new melanoma susceptibility loci

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.959

• Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers

  JNCI Journal of the National Cancer Institute · 2009 · https://doi.org/10.1093/jnci/djp473

Current projects

No projects listed.