David M. Kaye

Research interests

Publications

• Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease

  Circulation · 2020 · 10.1161/circulationaha.119.043081

• Alcohol Abstinence in Drinkers with Atrial Fibrillation

  New England Journal of Medicine · 2020 · 10.1056/nejmoa1817591

• Sex differences in heart failure

  European Heart Journal · 2019 · https://doi.org/10.1093/eurheartj/ehz835

• Implications of Underlying Mechanisms for the Recognition and Management of Diabetic Cardiomyopathy

  Journal of the American College of Cardiology · 2018 · 10.1016/j.jacc.2017.11.019

• Sex Differences in Cardiovascular Pathophysiology

  Circulation · 2018 · 10.1161/circulationaha.118.034271

• Beyond gut feelings: how the gut microbiota regulates blood pressure

  Nature Reviews Cardiology · 2017 · 10.1038/nrcardio.2017.120

• Catheter Ablation Versus Medical Rate Control in Atrial Fibrillation and Systolic Dysfunction

  Journal of the American College of Cardiology · 2017 · https://doi.org/10.1016/j.jacc.2017.08.041

• High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice

  Circulation · 2016 · https://doi.org/10.1161/circulationaha.116.024545

• A transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (REDUCE LAP-HF): a multicentre, open-label, single-arm, phase 1 trial

  The Lancet · 2016 · https://doi.org/10.1016/s0140-6736(16)00704-2

• Air Versus Oxygen in ST-Segment–Elevation Myocardial Infarction

  Circulation · 2015 · 10.1161/circulationaha.114.014494

• Refractory cardiac arrest treated with mechanical CPR, hypothermia, ECMO and early reperfusion (the CHEER trial)

  Resuscitation · 2014 · 10.1016/j.resuscitation.2014.09.010

• Cardiac Complications of Thoracic Irradiation

  Journal of the American College of Cardiology · 2013 · 10.1016/j.jacc.2013.01.090

• Treatment of Functional Mitral Regurgitation by Percutaneous Annuloplasty: Results of the TITAN Trial

  European Journal of Heart Failure · 2012 · https://doi.org/10.1093/eurjhf/hfs076

• NKX2-5eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes

  Nature Methods · 2011 · 10.1038/nmeth.1740

• Percutaneous Mitral Annuloplasty for Functional Mitral Regurgitation

  Circulation · 2009 · https://doi.org/10.1161/circulationaha.109.849885

• High-Density Lipoprotein Modulates Glucose Metabolism in Patients With Type 2 Diabetes Mellitus

  Circulation · 2009 · 10.1161/circulationaha.108.843219

• Evaluation of Diffuse Myocardial Fibrosis in Heart Failure With Cardiac Magnetic Resonance Contrast-Enhanced T1 Mapping

  Journal of the American College of Cardiology · 2008 · https://doi.org/10.1016/j.jacc.2008.06.049

• Controlled Trial of Continuous Positive Airway Pressure in Obstructive Sleep Apnea and Heart Failure

  American Journal of Respiratory and Critical Care Medicine · 2003 · 10.1164/rccm.200306-752oc

• Relation Between Cardiac Sympathetic Activity and Hypertensive Left Ventricular Hypertrophy

  Circulation · 2003 · 10.1161/01.cir.0000081775.72651.b6

• Sympathetic Augmentation in Hypertension

  Hypertension · 2003 · 10.1161/01.hyp.0000103160.35395.9e

• Effect of sunlight and season on serotonin turnover in the brain

  The Lancet · 2002 · https://doi.org/10.1016/s0140-6736(02)11737-5

• Neural mechanisms in human obesity-related hypertension

  Journal of Hypertension · 1999 · 10.1097/00004872-199917080-00012

• Influence of Pulmonary Capillary Wedge Pressure on Central Apnea in Heart Failure

  Circulation · 1999 · https://doi.org/10.1161/01.cir.99.12.1574

• Cardiac Sympathetic Nerve Function in Congestive Heart Failure

  Circulation · 1996 · 10.1161/01.cir.93.9.1667

• Nitric Oxide-dependent Parasympathetic Signaling Is Due to Activation of Constitutive Endothelial (Type III) Nitric Oxide Synthase in Cardiac Myocytes

  Journal of Biological Chemistry · 1995 · 10.1074/jbc.270.24.14582

• Adverse consequences of high sympathetic nervous activity in the failing human heart

  Journal of the American College of Cardiology · 1995 · https://doi.org/10.1016/0735-1097(95)00332-0

• Heart rate spectral analysis, cardiac norepinephrine spillover, and muscle sympathetic nerve activity during human sympathetic nervous activation and failure.

  Circulation · 1994 · 10.1161/01.cir.90.1.234

Current projects

No projects listed.