Stephen G. Waxman

Research interests

Publications

• The Role of Voltage-Gated Sodium Channels in Pain Signaling

  Physiological Reviews · 2019 · https://doi.org/10.1152/physrev.00052.2017

• Regulating excitability of peripheral afferents: emerging ion channel targets

  Nature Neuroscience · 2014 · 10.1038/nn.3602

• The NaV1.7 sodium channel: from molecule to man

  Nature reviews. Neuroscience · 2012 · https://doi.org/10.1038/nrn3404

• De Novo Pathogenic SCN8A Mutation Identified by Whole-Genome Sequencing of a Family Quartet Affected by Infantile Epileptic Encephalopathy and SUDEP

  The American Journal of Human Genetics · 2012 · 10.1016/j.ajhg.2012.01.006

• Gain-of-function Na v 1.8 mutations in painful neuropathy

  Proceedings of the National Academy of Sciences · 2012 · 10.1073/pnas.1216080109

• Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke

  Brain · 2011 · 10.1093/brain/awr063

• Gain of function Na V 1.7 mutations in idiopathic small fiber neuropathy

  Annals of Neurology · 2011 · 10.1002/ana.22485

• Sodium Channels in Normal and Pathological Pain

  Annual Review of Neuroscience · 2010 · 10.1146/annurev-neuro-060909-153234

• The roles of sodium channels in nociception: Implications for mechanisms of pain

  Pain · 2007 · 10.1016/j.pain.2007.07.026

• A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons

  Proceedings of the National Academy of Sciences · 2006 · 10.1073/pnas.0602813103

• Activated Microglia Contribute to the Maintenance of Chronic Pain after Spinal Cord Injury

  Journal of Neuroscience · 2006 · https://doi.org/10.1523/jneurosci.0003-06.2006

• Axonal conduction and injury in multiple sclerosis: the role of sodium channels

  Nature reviews. Neuroscience · 2006 · 10.1038/nrn2023

• Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons

  The Journal of Physiology · 2006 · 10.1113/jphysiol.2006.121483

• International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels

  Pharmacological Reviews · 2005 · https://doi.org/10.1124/pr.57.4.4

• Electrophysiological Properties of Mutant Na v 1.7 Sodium Channels in a Painful Inherited Neuropathy

  Journal of Neuroscience · 2004 · 10.1523/jneurosci.2695-04.2004

• Molecular changes in neurons in multiple sclerosis: Altered axonal expression of Na v 1.2 and Na v 1.6 sodium channels and Na + /Ca 2 + exchanger

  Proceedings of the National Academy of Sciences · 2004 · 10.1073/pnas.0402765101

• Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain

  Pain · 2004 · 10.1016/j.pain.2003.12.035

• Contribution of Na v 1.8 Sodium Channels to Action Potential Electrogenesis in DRG Neurons

  Journal of Neurophysiology · 2001 · 10.1152/jn.2001.86.2.629

• A Novel Persistent Tetrodotoxin-Resistant Sodium Current In SNS-Null And Wild-Type Small Primary Sensory Neurons

  Journal of Neuroscience · 1999 · 10.1523/jneurosci.19-24-j0001.1999

• NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy

  Proceedings of the National Academy of Sciences · 1998 · 10.1073/pnas.95.15.8963

• Slow Closed-State Inactivation: A Novel Mechanism Underlying Ramp Currents in Cells Expressing the hNE/PN1 Sodium Channel

  Journal of Neuroscience · 1998 · 10.1523/jneurosci.18-23-09607.1998

• Spinal Cord Reconstruction

  Trends in Neurosciences · 1983 · 10.1016/0166-2236(83)90228-x

• Determinants of conduction velocity in myelinated nerve fibers

  Muscle & Nerve · 1980 · https://doi.org/10.1002/mus.880030207

• The Interictal Behavior Syndrome of Temporal Lobe Epilepsy

  Archives of General Psychiatry · 1975 · 10.1001/archpsyc.1975.01760300118011

• Relative Conduction Velocities of Small Myelinated and Non-myelinated Fibres in the Central Nervous System

  Nature New Biology · 1972 · 10.1038/newbio238217a0

Current projects

No projects listed.