Simon H. S. Pearce

Research interests

Publications

• Adrenal insufficiency

  The Lancet · 2021 · https://doi.org/10.1016/s0140-6736(21)00136-7

• The 2021 European Group on Graves’ orbitopathy (EUGOGO) clinical practice guidelines for the medical management of Graves’ orbitopathy

  European Journal of Endocrinology · 2021 · https://doi.org/10.1530/eje-21-0479

• Mycophenolate plus methylprednisolone versus methylprednisolone alone in active, moderate-to-severe Graves' orbitopathy (MINGO): a randomised, observer-masked, multicentre trial

  The Lancet Diabetes & Endocrinology · 2018 · https://doi.org/10.1016/s2213-8587(18)30020-2

• 2018 European Thyroid Association Guideline for the Management of Graves’ Hyperthyroidism

  European Thyroid Journal · 2018 · https://doi.org/10.1159/000490384

• Thyroid hormones and cardiovascular disease

  Nature Reviews Cardiology · 2016 · https://doi.org/10.1038/nrcardio.2016.174

• 2013 ETA Guideline: Management of Subclinical Hypothyroidism

  European Thyroid Journal · 2013 · https://doi.org/10.1159/000356507

• A Review of the Clinical Consequences of Variation in Thyroid Function Within the Reference Range

  The Journal of Clinical Endocrinology & Metabolism · 2013 · https://doi.org/10.1210/jc.2013-1315

• Consensus statement on the diagnosis, treatment and follow‐up of patients with primary adrenal insufficiency

  Journal of Internal Medicine · 2013 · https://doi.org/10.1111/joim.12162

• Levothyroxine Treatment of Subclinical Hypothyroidism, Fatal and Nonfatal Cardiovascular Events, and Mortality

  Archives of Internal Medicine · 2012 · https://doi.org/10.1001/archinternmed.2012.1159

• Prevalence and Relative Risk of Other Autoimmune Diseases in Subjects with Autoimmune Thyroid Disease

  The American Journal of Medicine · 2010 · https://doi.org/10.1016/j.amjmed.2009.06.030

• Diagnosis and management of vitamin D deficiency

  BMJ · 2010 · https://doi.org/10.1136/bmj.b5664

• The Incidence of Ischemic Heart Disease and Mortality in People with Subclinical Hypothyroidism: Reanalysis of the Whickham Survey Cohort

  The Journal of Clinical Endocrinology & Metabolism · 2010 · https://doi.org/10.1210/jc.2009-1749

• Consensus Statement of the European Group on Graves' Orbitopathy (EUGOGO) on Management of Graves' Orbitopathy

  Thyroid · 2008 · https://doi.org/10.1089/thy.2007.0315

• Consensus statement of the European Group on Graves' orbitopathy (EUGOGO) on management of GO

  European Journal of Endocrinology · 2008 · https://doi.org/10.1530/eje-07-0666

• Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice

  Journal of Clinical Investigation · 2008 · https://doi.org/10.1172/jci34538

• The Influence of Age on the Relationship between Subclinical Hypothyroidism and Ischemic Heart Disease: A Metaanalysis

  The Journal of Clinical Endocrinology & Metabolism · 2008 · https://doi.org/10.1210/jc.2008-0167

• Reversal of Idiopathic Hypogonadotropic Hypogonadism

  New England Journal of Medicine · 2007 · https://doi.org/10.1056/nejmoa066494

• FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity

  Nature Genetics · 2007 · https://doi.org/10.1038/ng2046

• Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism

  Journal of Clinical Investigation · 2007 · https://doi.org/10.1172/jci29884

• Influences of Age, Gender, Smoking, and Family History on Autoimmune Thyroid Disease Phenotype

  The Journal of Clinical Endocrinology & Metabolism · 2006 · https://doi.org/10.1210/jc.2006-1402

• The Codon 620 Tryptophan Allele of the Lymphoid Tyrosine Phosphatase (LYP) Gene Is a Major Determinant of Graves’ Disease

  The Journal of Clinical Endocrinology & Metabolism · 2004 · https://doi.org/10.1210/jc.2004-1108

• Expression and Characterization of Inactivating and Activating Mutations in the Human Ca2+-sensing Receptor

  Journal of Biological Chemistry · 1996 · https://doi.org/10.1074/jbc.271.32.19537

• A Familial Syndrome of Hypocalcemia with Hypercalciuria Due to Mutations in the Calcium-Sensing Receptor

  New England Journal of Medicine · 1996 · https://doi.org/10.1056/nejm199610103351505

• A common molecular basis for three inherited kidney stone diseases

  Nature · 1996 · https://doi.org/10.1038/379445a0

• Calcium-sensing receptor mutations in familial benign hypercalcemia and neonatal hyperparathyroidism.

  Journal of Clinical Investigation · 1995 · https://doi.org/10.1172/jci118335

Current projects

No projects listed.