Andrew H. Wei

Research interests

Publications

• Acute myeloid leukaemia

  The Lancet · 2023 · 10.1016/s0140-6736(23)00108-3

• Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN

  Blood · 2022 · https://doi.org/10.1182/blood.2022016867

• International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data

  Blood · 2022 · https://doi.org/10.1182/blood.2022015850

• Towards precision medicine for AML

  Nature Reviews Clinical Oncology · 2021 · 10.1038/s41571-021-00509-w

• Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts

  The Lancet Haematology · 2020 · https://doi.org/10.1016/s2352-3026(20)30205-2

• Venetoclax plus LDAC for newly diagnosed AML ineligible for intensive chemotherapy: a phase 3 randomized placebo-controlled trial

  Blood · 2020 · https://doi.org/10.1182/blood.2020004856

• Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission

  New England Journal of Medicine · 2020 · https://doi.org/10.1056/nejmoa2004444

• Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia

  New England Journal of Medicine · 2020 · https://doi.org/10.1056/nejmoa2012971

• MDM2 inhibition: an important step forward in cancer therapy

  Leukemia · 2020 · 10.1038/s41375-020-0949-z

• Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML

  Blood · 2020 · 10.1182/blood.2019003988

• How I treat acute myeloid leukemia in the era of new drugs

  Blood · 2019 · 10.1182/blood.2019001239

• Venetoclax Combined With Low-Dose Cytarabine for Previously Untreated Patients With Acute Myeloid Leukemia: Results From a Phase Ib/II Study

  Journal of Clinical Oncology · 2019 · 10.1200/jco.18.01600

• BH3-Mimetic Drugs: Blazing the Trail for New Cancer Medicines

  Cancer Cell · 2018 · 10.1016/j.ccell.2018.11.004

• Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia

  Blood · 2018 · 10.1182/blood-2018-08-868752

• Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label, phase 1b study

  The Lancet Oncology · 2018 · 10.1016/s1470-2045(18)30010-x

• AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies

  Cancer Discovery · 2018 · 10.1158/2159-8290.cd-18-0387

• Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia

  New England Journal of Medicine · 2017 · 10.1056/nejmoa1609783

• Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

  New England Journal of Medicine · 2017 · https://doi.org/10.1056/nejmoa1614359

• Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML

  Cell stem cell · 2017 · https://doi.org/10.1016/j.stem.2017.11.006

• The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

  Nature · 2016 · 10.1038/nature19830

• Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

  Blood · 2016 · https://doi.org/10.1182/blood-2016-08-733196

• Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia

  Genes & Development · 2012 · 10.1101/gad.182980.111

• The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized

  Cancer Cell · 2006 · 10.1016/j.ccr.2006.08.027

• Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function

  Molecular Cell · 2005 · 10.1016/j.molcel.2004.12.030

• Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x L , but not Bcl-2, until displaced by BH3-only proteins

  Genes & Development · 2005 · 10.1101/gad.1304105

Current projects

No projects listed.