S. Mallal

Research interests

Publications

• RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors

  Clinical Cancer Research · 2015 · https://doi.org/10.1158/1078-0432.ccr-15-1125

• Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls

  PLoS Pathogens · 2013 · https://doi.org/10.1371/journal.ppat.1003515

• Influence of HLA-C Expression Level on HIV Control

  Science · 2013 · https://doi.org/10.1126/science.1232685

• Common Genetic Variation and the Control of HIV-1 in Humans

  PLoS Genetics · 2009 · https://doi.org/10.1371/journal.pgen.1000791

• Adaptation of HIV-1 to human leukocyte antigen class I

  Nature · 2009 · https://doi.org/10.1038/nature07746

• Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection

  Journal of Virology · 2008 · https://doi.org/10.1128/jvi.01041-08

• A Whole-Genome Association Study of Major Determinants for Host Control of HIV-1

  Science · 2007 · https://doi.org/10.1126/science.1143767

• Selective Escape from CD8 + T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution

  Journal of Virology · 2005 · https://doi.org/10.1128/jvi.79.21.13239-13249.2005

• Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes

  Nature Immunology · 2005 · https://doi.org/10.1038/ni1281

• Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA

  The Journal of Experimental Medicine · 2005 · https://doi.org/10.1084/jem.20041455

• Selection, Transmission, and Reversion of an Antigen-Processing Cytotoxic T-Lymphocyte Escape Mutation in Human Immunodeficiency Virus Type 1 Infection

  Journal of Virology · 2004 · https://doi.org/10.1128/jvi.78.13.7069-7078.2004

• Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA

  Nature · 2004 · https://doi.org/10.1038/nature03113

• HIV lipodystrophy: prevalence, severity and correlates of risk in Australia

  HIV Medicine · 2003 · https://doi.org/10.1046/j.1468-1293.2003.00159.x

• Effects of CCR5-Δ 32, CCR2-64I, and SDF-1 3′A Alleles on HIV-1 Disease Progression: An International Meta-Analysis of Individual-Patient Data

  Annals of Internal Medicine · 2001 · https://doi.org/10.7326/0003-4819-135-9-200111060-00008

Current projects

No projects listed.