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André B. P. Kuilenburg

Researcher Next ID · RN-033561

Researcher · Biochemistry, Genetics and Molecular Biology

Amsterdam Neuroscience

Amsterdam, Netherlands

Accepting doctoral researchersFunding unknown
Works count
1,756
Citation count
15,891
H-index
58
i10-index
224

Research interests

Biochemistry, Genetics and Molecular Biology
Medicine
Biochemical and Molecular Research
Metabolism and Genetic Disorders
Colorectal Cancer Treatments and Studies
Neonatal Health and Biochemistry
Cancer therapeutics and mechanisms

Publications

  • DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis

    The Lancet Oncology · 2018 · https://doi.org/10.1016/s1470-2045(18)30686-7

  • Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data

    The Lancet Oncology · 2015 · https://doi.org/10.1016/s1470-2045(15)00286-7

  • Thalassemia Syndromes

    Journal · 2009 · https://doi.org/10.1007/978-3-540-29676-8_1731

  • Histone deacetylases (HDACs): characterization of the classical HDAC family

    Biochemical Journal · 2003 · https://doi.org/10.1042/bj20021321

  • Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency.

    PubMed · 2001

  • Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency

    Human Genetics · 1999 · https://doi.org/10.1007/pl00008711

  • Reduced replication of 3TC‐resistant HIV‐1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.

    The EMBO Journal · 1996 · https://doi.org/10.1002/j.1460-2075.1996.tb00777.x

Current projects

    No projects listed.