Rob Pieters

Research interests

Publications

• Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized Study

  Journal of Clinical Oncology · 2019 · https://doi.org/10.1200/jco.19.00261

• Successful Therapy Reduction and Intensification for Childhood Acute Lymphoblastic Leukemia Based on Minimal Residual Disease Monitoring: Study ALL10 From the Dutch Childhood Oncology Group

  Journal of Clinical Oncology · 2016 · 10.1200/jco.2015.64.6364

• Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration

  Journal of Clinical Oncology · 2015 · https://doi.org/10.1200/jco.2014.59.1636

• NUP98/JARID1A is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX gene expression pattern

  Leukemia · 2013 · https://doi.org/10.1038/leu.2013.87

• Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL

  Blood · 2013 · https://doi.org/10.1182/blood-2012-10-462358

• Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study

  The Lancet Oncology · 2012 · 10.1016/s1470-2045(12)70377-7

• MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia

  Haematologica · 2011 · https://doi.org/10.3324/haematol.2010.026138

• Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

  Nature Genetics · 2011 · 10.1038/ng.924

• NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern

  Blood · 2011 · https://doi.org/10.1182/blood-2011-04-346643

• Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

  Cancer Cell · 2011 · 10.1016/j.ccr.2011.02.008

• Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)–rearranged acute lymphoblastic leukemia: results from the Interfant-99 Study

  Blood · 2010 · https://doi.org/10.1182/blood-2010-03-273532

• L‐asparaginase treatment in acute lymphoblastic leukemia

  Cancer · 2010 · 10.1002/cncr.25489

• Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18–20 September 2008

  Leukemia · 2009 · https://doi.org/10.1038/leu.2009.268

• Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study

  Blood · 2009 · https://doi.org/10.1182/blood-2009-04-215152

• A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

  The Lancet Oncology · 2009 · https://doi.org/10.1016/s1470-2045(08)70339-5

• Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells

  Blood · 2008 · https://doi.org/10.1182/blood-2008-05-157842

• Favorable prognostic impact of NPM1 gene mutations in childhood acute myeloid leukemia, with emphasis on cytogenetically normal AML

  Leukemia · 2008 · https://doi.org/10.1038/leu.2008.313

• A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial

  The Lancet · 2007 · https://doi.org/10.1016/s0140-6736(07)61126-x

• FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors

  The Journal of Experimental Medicine · 2007 · https://doi.org/10.1084/jem.20070876

• Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

  Nature Genetics · 2007 · https://doi.org/10.1038/ng2025

• Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance

  Cancer Cell · 2006 · 10.1016/j.ccr.2006.09.006

• The MLL recombinome of acute leukemias

  Leukemia · 2006 · https://doi.org/10.1038/sj.leu.2404150

• Gene-Expression Patterns in Drug-Resistant Acute Lymphoblastic Leukemia Cells and Response to Treatment

  New England Journal of Medicine · 2004 · https://doi.org/10.1056/nejmoa033513

• Significant difference in outcome for adolescents with acute lymphoblastic leukemia treated on pediatric vs adult protocols in the Netherlands

  Leukemia · 2004 · 10.1038/sj.leu.2403538

• Inhibition of FLT3 in MLL

  Cancer Cell · 2003 · 10.1016/s1535-6108(03)00003-5

• MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

  Nature Genetics · 2001 · https://doi.org/10.1038/ng765

• Biological and therapeutic aspects of infant leukemia

  Blood · 2000 · 10.1182/blood.v96.1.24

Current projects

No projects listed.