Toin H. Van Kuppevelt

Research interests

Publications

• Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

  Proceedings of the National Academy of Sciences · 2013 · https://doi.org/10.1073/pnas.1304266110

• Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice

  Diabetes · 2011 · https://doi.org/10.2337/db11-1024

• Parietal Epithelial Cells Participate in the Formation of Sclerotic Lesions in Focal Segmental Glomerulosclerosis

  Journal of the American Society of Nephrology · 2011 · https://doi.org/10.1681/asn.2010090970

• The performance of human dental pulp stem cells on different three-dimensional scaffold materials

  Biomaterials · 2006 · https://doi.org/10.1016/j.biomaterials.2006.07.013

• Increased angiogenesis and blood vessel maturation in acellular collagen–heparin scaffolds containing both FGF2 and VEGF

  Biomaterials · 2006 · https://doi.org/10.1016/j.biomaterials.2006.10.029

• Chondroitin 6‐sulphate synthesis is up‐regulated in injured CNS, induced by injury‐related cytokines and enhanced in axon‐growth inhibitory glia

  European Journal of Neuroscience · 2005 · https://doi.org/10.1111/j.1460-9568.2005.03876.x

• Disruption of Abcc6 in the mouse: novel insight in the pathogenesis of pseudoxanthoma elasticum

  Human Molecular Genetics · 2005 · https://doi.org/10.1093/hmg/ddi183

• Cellular Binding of Hepatitis C Virus Envelope Glycoprotein E2 Requires Cell Surface Heparan Sulfate

  Journal of Biological Chemistry · 2003 · https://doi.org/10.1074/jbc.m302267200

• Large, Tissue-regulated Domain Diversity of Heparan Sulfates Demonstrated by Phage Display Antibodies

  Journal of Biological Chemistry · 2002 · https://doi.org/10.1074/jbc.m104852200

• Interaction of chondrocytes, extracellular matrix and growth factors: relevance for articular cartilage tissue engineering

  Osteoarthritis and Cartilage · 2002 · https://doi.org/10.1053/joca.2002.0806

• Loading of collagen‐heparan sulfate matrices with bFGF promotes angiogenesis and tissue generation in rats

  Journal of Biomedical Materials Research · 2002 · https://doi.org/10.1002/jbm.10267

• Crosslinked type II collagen matrices: preparation, characterization, and potential for cartilage engineering

  Biomaterials · 2002 · https://doi.org/10.1016/s0142-9612(02)00067-4

• Linkage of chondroitin-sulfate to type I collagen scaffolds stimulates the bioactivity of seeded chondrocytes in vitro

  Biomaterials · 2001 · https://doi.org/10.1016/s0142-9612(00)00423-3

• Development of tailor-made collagen–glycosaminoglycan matrices: EDC/NHS crosslinking, and ultrastructural aspects

  Biomaterials · 2000 · https://doi.org/10.1016/s0142-9612(99)00222-7

• Defective Heparan Sulfate Biosynthesis and Neonatal Lethality in Mice LackingN-Deacetylase/N-Sulfotransferase-1

  Journal of Biological Chemistry · 2000 · https://doi.org/10.1074/jbc.c000359200

• Generation and Application of Type-specific Anti-Heparan Sulfate Antibodies Using Phage Display Technology

  Journal of Biological Chemistry · 1998 · https://doi.org/10.1074/jbc.273.21.12960

Current projects

No projects listed.