Nico Vermeulen

Researcher Next ID · RN-033716

Researcher · Biochemistry, Genetics and Molecular Biology

Vrije Universiteit Amsterdam

Amsterdam, Netherlands

Accepting doctoral researchersFunding unknown

Works count: 852
Citation count: 24,022
H-index: 64
i10-index: 342

Research interests

Biochemistry, Genetics and Molecular Biology

Chemistry

Computer Science

Medicine

Pharmacogenetics and Drug Metabolism

Computational Drug Discovery Methods

Analytical Chemistry and Chromatography

Drug Transport and Resistance Mechanisms

Glutathione Transferases and Polymorphisms

Publications

Managing the challenge of chemically reactive metabolites in drug development
Nature Reviews Drug Discovery · 2011 · 10.1038/nrd3408
Cytochrome P450 in Silico: An Integrative Modeling Approach
Journal of Medicinal Chemistry · 2005 · https://doi.org/10.1021/jm040180d
Enzyme-Catalyzed Activation of Anticancer Prodrugs
Pharmacological Reviews · 2004 · https://doi.org/10.1124/pr.56.1.3
Fish bioaccumulation and biomarkers in environmental risk assessment: a review
Environmental Toxicology and Pharmacology · 2002 · https://doi.org/10.1016/s1382-6689(02)00126-6
Paracetamol (Acetaminophen)-Induced Toxicity: Molecular and Biochemical Mechanisms, Analogues and Protective Approaches
Critical Reviews in Toxicology · 2001 · https://doi.org/10.1080/20014091111677
Genetic Polymorphisms of Human N -Acetyltransferase, Cytochrome P450, Glutathione-S-Transferase, and Epoxide Hydrolase Enzymes: Relevance to Xenobiotic Metabolism and Toxicity
Critical Reviews in Toxicology · 1999 · 10.1080/10408449991349186
Biomarkers of free radical damage
Free Radical Biology and Medicine · 1999 · https://doi.org/10.1016/s0891-5849(98)00196-8
Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver
Biochemical Pharmacology · 1996 · 10.1016/0006-2952(95)02113-2
Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates. Role in bioactivation and detoxication mechanisms of xenobiotics.
Pharmacological Reviews · 1995 · 10.1016/s0031-6997(25)06846-2
Oxygen and Xenobiotic Reductase Activities of Cytochrome P450
Critical Reviews in Toxicology · 1995 · 10.3109/10408449509089886
Molecular Aspects of Paracetamol-Induced Hepatotoxicity and its Mechanism-Based Prevention
Drug Metabolism Reviews · 1992 · 10.3109/03602539208996298
Comprehensive medicinal chemistry
Trends in Pharmacological Sciences · 1991 · https://doi.org/10.1016/0165-6147(91)90535-z
Abstract of papers
Pharmacy World & Science · 1987 · https://doi.org/10.1007/bf01956491

Current projects

No projects listed.