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Taco W. Kuijpers

Researcher Next ID · RN-033725

Researcher · Biochemistry, Genetics and Molecular Biology

Amsterdam UMC Location University of Amsterdam

Amsterdam, Netherlands

Accepting doctoral researchersFunding unknown
Works count
837
Citation count
39,236
H-index
106
i10-index
500

Research interests

Biochemistry, Genetics and Molecular Biology
Immunology and Microbiology
Medicine
Immunodeficiency and Autoimmune Disorders
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Blood disorders and treatments
Kawasaki Disease and Coronary Complications
Immune Cell Function and Interaction

Publications

  • Acute Cardiovascular Manifestations in 286 Children With Multisystem Inflammatory Syndrome Associated With COVID-19 Infection in Europe

    Circulation · 2020 · https://doi.org/10.1161/circulationaha.120.050065

  • Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis

    Cell Reports · 2018 · 10.1016/j.celrep.2018.05.082

  • Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans

    Journal of Allergy and Clinical Immunology · 2018 · 10.1016/j.jaci.2018.01.039

  • Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans

    Journal of Allergy and Clinical Immunology · 2018 · 10.1016/j.jaci.2018.01.039

  • Decoding the Human Immunoglobulin G-Glycan Repertoire Reveals a Spectrum of Fc-Receptor- and Complement-Mediated-Effector Activities

    Frontiers in Immunology · 2017 · 10.3389/fimmu.2017.00877

  • The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

    Cell · 2016 · https://doi.org/10.1016/j.cell.2016.10.042

  • Mesenchymal Inflammation Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Disease Evolution in Human Pre-leukemia

    Cell stem cell · 2016 · 10.1016/j.stem.2016.08.021

  • Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells

    Cell · 2016 · https://doi.org/10.1016/j.cell.2016.10.026

  • DOCK8 Deficiency: Clinical and Immunological Phenotype and Treatment Options - a Review of 136 Patients

    Journal of Clinical Immunology · 2015 · 10.1007/s10875-014-0126-0

  • Clinical picture and treatment of 2212 patients with common variable immunodeficiency

    Journal of Allergy and Clinical Immunology · 2014 · https://doi.org/10.1016/j.jaci.2013.12.1077

  • Invasive fungal infection and impaired neutrophil killing in human CARD9 deficiency

    Blood · 2013 · 10.1182/blood-2012-08-450551

  • Mg 2+ Regulates Cytotoxic Functions of NK and CD8 T Cells in Chronic EBV Infection Through NKG2D

    Science · 2013 · 10.1126/science.1240094

  • CD47–signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction

    Proceedings of the National Academy of Sciences · 2011 · 10.1073/pnas.1106550108

  • Draft consensus guidelines for diagnosis and treatment of Shwachman‐Diamond syndrome

    Annals of the New York Academy of Sciences · 2011 · 10.1111/j.1749-6632.2011.06349.x

  • Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

    Cell Death and Differentiation · 2011 · https://doi.org/10.1038/cdd.2011.1

  • Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease

    Nature Genetics · 2011 · 10.1038/ng.981

  • Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease

    Nature Genetics · 2010 · 10.1038/ng.640

  • Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species

    Proceedings of the National Academy of Sciences · 2010 · 10.1073/pnas.1012016107

  • A Genome-Wide Association Study Identifies Novel and Functionally Related Susceptibility Loci for Kawasaki Disease

    PLoS Genetics · 2009 · https://doi.org/10.1371/journal.pgen.1000319

  • Chronic Granulomatous Disease: The European Experience

    PLoS ONE · 2009 · https://doi.org/10.1371/journal.pone.0005234

  • CD20 deficiency in humans results in impaired T cell–independent antibody responses

    Journal of Clinical Investigation · 2009 · 10.1172/jci40231

  • Human NK cells can control CMV infection in the absence of T cells

    Blood · 2008 · 10.1182/blood-2008-05-157354

  • Infiltrated Neutrophils Acquire Novel Chemokine Receptor Expression and Chemokine Responsiveness in Chronic Inflammatory Lung Diseases

    The Journal of Immunology · 2008 · 10.4049/jimmunol.181.11.8053

  • Functional characterization of mitochondria in neutrophils: a role restricted to apoptosis

    Cell Death and Differentiation · 2003 · 10.1038/sj.cdd.4401320

  • Leukocyte adhesion deficiency type 1 (LAD-1)/variant. A novel immunodeficiency syndrome characterized by dysfunctional beta2 integrins.

    Journal of Clinical Investigation · 1997 · 10.1172/jci119697

Current projects

    No projects listed.