Jelle Wesseling

Research interests

Publications

• Personalized early detection and prevention of breast cancer: ENVISION consensus statement

  Nature Reviews Clinical Oncology · 2020 · https://doi.org/10.1038/s41571-020-0388-9

• Ductal carcinoma in situ: to treat or not to treat, that is the question

  British Journal of Cancer · 2019 · 10.1038/s41416-019-0478-6

• Proteomic profiling of extracellular vesicles allows for human breast cancer subtyping

  Communications Biology · 2019 · 10.1038/s42003-019-0570-8

• Neoadjuvant chemotherapy with or without anthracyclines in the presence of dual HER2 blockade for HER2-positive breast cancer (TRAIN-2): a multicentre, open-label, randomised, phase 3 trial

  The Lancet Oncology · 2018 · https://doi.org/10.1016/s1470-2045(18)30570-9

• Tumour-specific proline vulnerability uncovered by differential ribosome codon reading

  Nature · 2016 · 10.1038/nature16982

• Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer

  Scientific Reports · 2016 · 10.1038/srep18517

• Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer

  JNCI Journal of the National Cancer Institute · 2016 · 10.1093/jnci/djw148

• Feasibility of a prospective, randomised, open-label, international multicentre, phase III, non-inferiority trial to assess the safety of active surveillance for low risk ductal carcinoma in situ – The LORD study

  European Journal of Cancer · 2015 · 10.1016/j.ejca.2015.05.008

• Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration

  Annals of Oncology · 2015 · 10.1093/annonc/mdv161

• Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma

  Nature · 2014 · https://doi.org/10.1038/nature13121

• Marking Axillary Lymph Nodes With Radioactive Iodine Seeds for Axillary Staging After Neoadjuvant Systemic Treatment in Breast Cancer Patients

  Annals of Surgery · 2014 · 10.1097/sla.0000000000000558

• A prospective evaluation of a breast cancer prognosis signature in the observational RASTER study

  International Journal of Cancer · 2013 · 10.1002/ijc.28082

• Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers

  British Journal of Cancer · 2013 · 10.1038/bjc.2013.144

• Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

  Human Mutation · 2011 · https://doi.org/10.1002/humu.21633

• Magnetic Resonance Imaging Response Monitoring of Breast Cancer During Neoadjuvant Chemotherapy: Relevance of Breast Cancer Subtype

  Journal of Clinical Oncology · 2011 · 10.1200/jco.2010.31.1258

• Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies

  PLoS Medicine · 2010 · https://doi.org/10.1371/journal.pmed.1000279

• Receptor conversion in distant breast cancer metastases

  Breast Cancer Research · 2010 · 10.1186/bcr2645

• An aCGH classifier derived from BRCA1-mutated breast cancer and benefit of high-dose platinum-based chemotherapy in HER2-negative breast cancer patients

  Annals of Oncology · 2010 · 10.1093/annonc/mdq624

• The 70-gene signature as a response predictor for neoadjuvant chemotherapy in breast cancer

  Breast Cancer Research and Treatment · 2009 · 10.1007/s10549-009-0333-1

• Gene Expression Profiling to Identify the Histogenetic Origin of Metastatic Adenocarcinomas of Unknown Primary

  Journal of Clinical Oncology · 2008 · 10.1200/jco.2007.14.6969

• Use of 70-gene signature to predict prognosis of patients with node-negative breast cancer: a prospective community-based feasibility study (RASTER)

  The Lancet Oncology · 2007 · 10.1016/s1470-2045(07)70346-7

• Increased risk of fundic gland polyps during long‐term proton pump inhibitor therapy

  Alimentary Pharmacology & Therapeutics · 2006 · 10.1111/j.1365-2036.2006.03127.x

• Tissue Distribution of the Death Ligand TRAIL and Its Receptors

  Journal of Histochemistry & Cytochemistry · 2004 · 10.1369/jhc.3a6112.2004

• A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.

  Molecular Biology of the Cell · 1996 · 10.1091/mbc.7.4.565

• Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix components.

  The Journal of Cell Biology · 1995 · https://doi.org/10.1083/jcb.129.1.255

Current projects

No projects listed.