Geert‐Jan Boons

Research interests

Publications

• Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2

  Nature Chemical Biology · 2021 · 10.1038/s41589-021-00924-1

• Heparan Sulfate Proteoglycans as Attachment Factor for SARS-CoV-2

  ACS Central Science · 2021 · 10.1021/acscentsci.1c00010

• Human coronaviruses OC43 and HKU1 bind to 9- O -acetylated sialic acids via a conserved receptor-binding site in spike protein domain A

  Proceedings of the National Academy of Sciences · 2019 · https://doi.org/10.1073/pnas.1809667116

• Structural basis for human coronavirus attachment to sialic acid receptors

  Nature Structural & Molecular Biology · 2019 · https://doi.org/10.1038/s41594-019-0233-y

• Advancing Solutions to the Carbohydrate Sequencing Challenge

  Journal of the American Chemical Society · 2019 · https://doi.org/10.1021/jacs.9b06406

• Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives

  Journal of Extracellular Vesicles · 2018 · 10.1080/20013078.2018.1442985

• A General Strategy for the Chemoenzymatic Synthesis of Asymmetrically Branched N -Glycans

  Science · 2013 · 10.1126/science.1236231

• Adaptive immune activation: glycosylation does matter

  Nature Chemical Biology · 2013 · 10.1038/nchembio.1403

• Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine

  Proceedings of the National Academy of Sciences · 2011 · 10.1073/pnas.1115166109

• Strain‐Promoted Alkyne–Azide Cycloadditions (SPAAC) Reveal New Features of Glycoconjugate Biosynthesis

  ChemBioChem · 2011 · 10.1002/cbic.201100117

• Metal-Free Sequential [3 + 2]-Dipolar Cycloadditions using Cyclooctynes and 1,3-Dipoles of Different Reactivity

  Journal of the American Chemical Society · 2010 · 10.1021/ja1081519

• Protein Modification by Strain‐Promoted Alkyne–Nitrone Cycloaddition

  Angewandte Chemie International Edition · 2010 · 10.1002/anie.201000408

• Modular Synthesis of Heparan Sulfate Oligosaccharides for Structure−Activity Relationship Studies

  Journal of the American Chemical Society · 2009 · 10.1021/ja907358k

• Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research

  Nature Chemistry · 2009 · https://doi.org/10.1038/nchem.399

• Selective Labeling of Living Cells by a Photo-Triggered Click Reaction

  Journal of the American Chemical Society · 2009 · https://doi.org/10.1021/ja9054096

• Immunotherapy for cancer: synthetic carbohydrate-based vaccines

  Chemical Communications · 2009 · 10.1039/b908664c

• Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper‐Free and Fast Huisgen Cycloadditions

  Angewandte Chemie International Edition · 2008 · https://doi.org/10.1002/anie.200705456

• Robust immune responses elicited by a fully synthetic three-component vaccine

  Nature Chemical Biology · 2007 · 10.1038/nchembio.2007.25

• A General Strategy for Stereoselective Glycosylations

  Journal of the American Chemical Society · 2005 · 10.1021/ja052548h

• An Angiogenic Switch in Macrophages Involving Synergy between Toll-Like Receptors 2, 4, 7, and 9 and Adenosine A2A Receptors

  American Journal Of Pathology · 2003 · 10.1016/s0002-9440(10)63698-x

• Recent Advances in O-Sialylation

  Chemical Reviews · 2000 · 10.1021/cr990313g

• Stereoselective 1,2-cis-galactosylation assisted by remote neighboring group participation and solvent effects

  Tetrahedron Letters · 1999 · 10.1016/s0040-4039(99)01203-4

• Solvent and Other Effects on the Stereoselectivity of Thioglycoside Glycosidations

  Synlett · 1997 · 10.1055/s-1997-5762

• Strategies in Oligosaccharide Synthesis

  Tetrahedron · 1996 · 10.1016/0040-4020(95)00897-7

Current projects

No projects listed.