Gerhard Rogler

Research interests

Publications

• Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries

  Nature Genetics · 2023 · https://doi.org/10.1038/s41588-023-01384-0

• Filgotinib as induction and maintenance therapy for ulcerative colitis (SELECTION): a phase 2b/3 double-blind, randomised, placebo-controlled trial

  The Lancet · 2021 · https://doi.org/10.1016/s0140-6736(21)00666-8

• Extraintestinal Manifestations of Inflammatory Bowel Disease: Current Concepts, Treatment, and Implications for Disease Management

  Gastroenterology · 2021 · https://doi.org/10.1053/j.gastro.2021.07.042

• Selecting End Points for Disease-Modification Trials in Inflammatory Bowel Disease: the SPIRIT Consensus From the IOIBD

  Gastroenterology · 2021 · https://doi.org/10.1053/j.gastro.2020.10.065

• Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance

  Cell stem cell · 2020 · https://doi.org/10.1016/j.stem.2020.02.007

• Dietary Guidance From the International Organization for the Study of Inflammatory Bowel Diseases

  Clinical Gastroenterology and Hepatology · 2020 · https://doi.org/10.1016/j.cgh.2020.01.046

• Deep Remission at 1 Year Prevents Progression of Early Crohn’s Disease

  Gastroenterology · 2020 · https://doi.org/10.1053/j.gastro.2020.03.039

• Microbial network disturbances in relapsing refractory Crohn’s disease

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-018-0308-z

• Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis

  Cell · 2018 · https://doi.org/10.1016/j.cell.2018.08.011

• An expert consensus to standardise definitions, diagnosis and treatment targets for anti‐fibrotic stricture therapies in Crohn's disease

  Alimentary Pharmacology & Therapeutics · 2018 · https://doi.org/10.1111/apt.14853

• Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders

  Frontiers in Psychiatry · 2018 · https://doi.org/10.3389/fpsyt.2018.00044

• Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation

  Nature Communications · 2017 · https://doi.org/10.1038/s41467-017-00213-3

• Iron deficiency across chronic inflammatory conditions: International expert opinion on definition, diagnosis, and management

  American Journal of Hematology · 2017 · 10.1002/ajh.24820

• Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome

  Gut · 2016 · https://doi.org/10.1136/gutjnl-2015-310297

• Development of an index to define overall disease severity in IBD

  Gut · 2016 · https://doi.org/10.1136/gutjnl-2016-312648

• 3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn’s Disease 2016: Part 2: Surgical Management and Special Situations

  Journal of Crohn s and Colitis · 2016 · https://doi.org/10.1093/ecco-jcc/jjw169

• Mechanisms, Management, and Treatment of Fibrosis in Patients With Inflammatory Bowel Diseases

  Gastroenterology · 2016 · https://doi.org/10.1053/j.gastro.2016.09.047

• European Evidence-based Consensus: Inflammatory Bowel Disease and Malignancies

  Journal of Crohn s and Colitis · 2015 · https://doi.org/10.1093/ecco-jcc/jjv141

• Chronological Order of Appearance of Extraintestinal Manifestations Relative to the Time of IBD Diagnosis in the Swiss Inflammatory Bowel Disease Cohort

  Inflammatory Bowel Diseases · 2015 · https://doi.org/10.1097/mib.0000000000000429

• Extraintestinal Manifestations of Inflammatory Bowel Disease

  Inflammatory Bowel Diseases · 2015 · https://doi.org/10.1097/mib.0000000000000392

• Deviations in human gut microbiota: a novel diagnostic test for determining dysbiosis in patients with IBS or IBD

  Alimentary Pharmacology & Therapeutics · 2015 · https://doi.org/10.1111/apt.13236

• Chronic ulcerative colitis and colorectal cancer

  Cancer Letters · 2013 · https://doi.org/10.1016/j.canlet.2013.07.032

• Imaging techniques for assessment of inflammatory bowel disease: Joint ECCO and ESGAR evidence-based consensus guidelines

  Journal of Crohn s and Colitis · 2013 · https://doi.org/10.1016/j.crohns.2013.02.020

• Smoking Cessation Induces Profound Changes in the Composition of the Intestinal Microbiota in Humans

  PLoS ONE · 2013 · https://doi.org/10.1371/journal.pone.0059260

• Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 3: Special situations

  Journal of Crohn s and Colitis · 2012 · https://doi.org/10.1016/j.crohns.2012.09.005

• The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis

  Journal of Crohn s and Colitis · 2010 · https://doi.org/10.1016/j.crohns.2009.12.003

• Frequency and Risk Factors for Extraintestinal Manifestations in the Swiss Inflammatory Bowel Disease Cohort

  The American Journal of Gastroenterology · 2010 · https://doi.org/10.1038/ajg.2010.343

• Probiotic Escherichia coli Nissle 1917 Inhibits Leaky Gut by Enhancing Mucosal Integrity

  PLoS ONE · 2007 · https://doi.org/10.1371/journal.pone.0001308

• Wound healing and fibrosis in intestinal disease

  Gut · 2006 · https://doi.org/10.1136/gut.2006.090456

• Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation

  Gastroenterology · 2002 · https://doi.org/10.1053/gast.2002.33662

• Cytokines in Inflammatory Bowel Disease

  World Journal of Surgery · 1998 · https://doi.org/10.1007/s002689900401

• Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

  Gastroenterology · 1998 · https://doi.org/10.1016/s0016-5085(98)70202-1

• Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion.

  Journal of Clinical Investigation · 1996 · https://doi.org/10.1172/jci118598

Current projects

No projects listed.