Dario Neri

Research interests

Publications

• DNA-Encoded Chemical Libraries: A Comprehensive Review with Succesful Stories and Future Challenges

  ACS Pharmacology & Translational Science · 2021 · 10.1021/acsptsci.1c00118

• DNA-Encoded Chemical Libraries: A Selection System Based on Endowing Organic Compounds with Amplifiable Information

  Annual Review of Biochemistry · 2018 · 10.1146/annurev-biochem-062917-012550

• Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation

  Nature Chemistry · 2015 · 10.1038/nchem.2158

• Recent advances in osteosarcoma

  Current Opinion in Pharmacology · 2014 · 10.1016/j.coph.2014.02.002

• A Small‐Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing Tumors

  Angewandte Chemie International Edition · 2014 · 10.1002/anie.201310709

• DNA-Encoded Chemical Libraries: Advancing beyond Conventional Small-Molecule Libraries

  Accounts of Chemical Research · 2014 · 10.1021/ar400284t

• Antibody–drug conjugates: Basic concepts, examples and future perspectives

  Journal of Controlled Release · 2012 · 10.1016/j.jconrel.2012.01.026

• Interfering with pH regulation in tumours as a therapeutic strategy

  Nature Reviews Drug Discovery · 2011 · https://doi.org/10.1038/nrd3554

• A Portable Albumin Binder from a DNA‐Encoded Chemical Library

  Angewandte Chemie International Edition · 2008 · 10.1002/anie.200704936

• A high‐affinity human monoclonal antibody specific to the alternatively spliced EDA domain of fibronectin efficiently targets tumor neo‐vasculature in vivo

  International Journal of Cancer · 2008 · 10.1002/ijc.23408

• High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries

  Proceedings of the National Academy of Sciences · 2008 · 10.1073/pnas.0805130105

• The Extra-domain A of Fibronectin Is a Vascular Marker of Solid Tumors and Metastases

  Cancer Research · 2007 · 10.1158/0008-5472.can-07-1436

• Tumour vascular targeting

  Nature reviews. Cancer · 2005 · https://doi.org/10.1038/nrc1627

• Fibronectin as target for tumor therapy

  International Journal of Cancer · 2005 · 10.1002/ijc.21677

• Encoded self-assembling chemical libraries

  Nature Biotechnology · 2004 · 10.1038/nbt961

• Selective targeted delivery of TNFα to tumor blood vessels

  Blood · 2003 · 10.1182/blood-2003-04-1039

• Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer.

  PubMed · 2003

• Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature

  Nature Biotechnology · 2002 · 10.1038/nbt0302-264

• Enhancement of the antitumor properties of interleukin-2 by its targeted delivery to the tumor blood vessel extracellular matrix

  Blood · 2002 · 10.1182/blood.v99.5.1659

• Selective targeting of tumoral vasculature: Comparison of different formats of an antibody (L19) to the ED‐B domain of fibronectin

  International Journal of Cancer · 2002 · 10.1002/ijc.10662

• Targeted delivery of tissue factor to the ED-B domain of fibronectin, a marker of angiogenesis, mediates the infarction of solid tumors in mice.

  PubMed · 2001

• Design and Use of a Phage Display Library

  Journal of Biological Chemistry · 1998 · https://doi.org/10.1074/jbc.273.34.21769

• Targeting by affinity–matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform

  Nature Biotechnology · 1997 · 10.1038/nbt1197-1271

• NMR Determination of Residual Structure in a Urea-Denatured Protein, the 434-Repressor

  Science · 1992 · https://doi.org/10.1126/science.1523410

• Stereospecific nuclear magnetic resonance assignments of the methyl groups of valine and leucine in the DNA-binding domain of the 434 repressor by biosynthetically directed fractional carbon-13 labeling

  Biochemistry · 1989 · https://doi.org/10.1021/bi00445a003

Current projects

No projects listed.