Thomas Ruzicka

Research interests

Publications

• Nemolizumab in patients with moderate-to-severe atopic dermatitis: Randomized, phase II, long-term extension study

  Journal of Allergy and Clinical Immunology · 2018 · https://doi.org/10.1016/j.jaci.2018.03.018

• Anti–Interleukin-31 Receptor A Antibody for Atopic Dermatitis

  New England Journal of Medicine · 2017 · https://doi.org/10.1056/nejmoa1606490

• Superiority of ivermectin 1% cream over metronidazole 0·75% cream in treating inflammatory lesions of rosacea: a randomized, investigator-blinded trial

  British Journal of Dermatology · 2014 · https://doi.org/10.1111/bjd.13408

• Schnitzler's syndrome: diagnosis, treatment, and follow‐up

  Allergy · 2013 · https://doi.org/10.1111/all.12129

• Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH)–a new autoinflammatory syndrome distinct from PAPA syndrome

  Journal of the American Academy of Dermatology · 2011 · 10.1016/j.jaad.2010.12.025

• Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions

  Science Translational Medicine · 2011 · 10.1126/scitranslmed.3002001

• Hypertrophic Scarring and Keloids: Pathomechanisms and Current and Emerging Treatment Strategies

  Molecular Medicine · 2010 · https://doi.org/10.2119/molmed.2009.00153

• Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon–independent apoptosis in human melanoma cells

  Journal of Clinical Investigation · 2009 · 10.1172/jci37155

• Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial

  British Journal of Dermatology · 2008 · https://doi.org/10.1111/j.1365-2133.2008.08487.x

• A Comparison of Oral Methylprednisolone Plus Azathioprine or Mycophenolate Mofetil for the Treatment of Bullous Pemphigoid

  Archives of Dermatology · 2007 · https://doi.org/10.1001/archderm.143.12.1536

• A Comparison of Oral Methylprednisolone Plus Azathioprine or Mycophenolate Mofetil for the Treatment of Pemphigus

  Archives of Dermatology · 2006 · https://doi.org/10.1001/archderm.142.11.1447

• Handbook of Atopic Eczema

  · 2006 · 10.1007/3-540-29856-8

• Epigenetic Silencing of the PTEN Gene in Melanoma

  Cancer Research · 2006 · 10.1158/0008-5472.can-06-0384

• IL-31: A new link between T cells and pruritus in atopic skin inflammation

  Journal of Allergy and Clinical Immunology · 2006 · https://doi.org/10.1016/j.jaci.2005.10.033

• Loss-of-Function Mutations in the Keratin 5 Gene Lead to Dowling-Degos Disease

  The American Journal of Human Genetics · 2006 · 10.1086/500850

• Somatic mutations in thePTCH,SMOH,SUFUHandTP53genes in sporadic basal cell carcinomas

  British Journal of Dermatology · 2005 · 10.1111/j.1365-2133.2005.06353.x

• Adverse effects of topical glucocorticosteroids

  Journal of the American Academy of Dermatology · 2005 · https://doi.org/10.1016/j.jaad.2005.01.010

• Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia

  The American Journal of Human Genetics · 2005 · https://doi.org/10.1086/431425

• Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone butyrate ointment in adult patients with atopic dermatitis

  Journal of Allergy and Clinical Immunology · 2002 · 10.1067/mai.2002.121832

• Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone acetate ointment in children with atopic dermatitis

  Journal of Allergy and Clinical Immunology · 2002 · https://doi.org/10.1067/mai.2002.121831

• CCL27–CCR10 interactions regulate T cell–mediated skin inflammation

  Nature Medicine · 2002 · https://doi.org/10.1038/nm0202-157

• Update on Kaposi's sarcoma and other HHV8 associated diseases. Part 1: epidemiology, environmental predispositions, clinical manifestations, and therapy

  The Lancet Infectious Diseases · 2002 · 10.1016/s1473-3099(02)00263-3

• Cutting Edge: The Orphan Chemokine Receptor G Protein-Coupled Receptor-2 (GPR-2, CCR10) Binds the Skin-Associated Chemokine CCL27 (CTACK/ALP/ILC)

  The Journal of Immunology · 2000 · 10.4049/jimmunol.164.7.3465

• Enzyme plus light therapy to repair DNA damage in ultraviolet-B-irradiated human skin

  Proceedings of the National Academy of Sciences · 2000 · 10.1073/pnas.030528897

• Up-Regulation of Macrophage Inflammatory Protein-3α/CCL20 and CC Chemokine Receptor 6 in Psoriasis

  The Journal of Immunology · 2000 · 10.4049/jimmunol.164.12.6621

• Singlet Oxygen Mediates the UVA-induced Generation of the Photoaging-associated Mitochondrial Common Deletion

  Journal of Biological Chemistry · 1999 · 10.1074/jbc.274.22.15345

• Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system.

  PubMed · 1998

• Photodynamic Therapy in Dermatology

  Archives of Dermatology · 1998 · 10.1001/archderm.134.2.207

• Evidence that Singlet Oxygen-induced Human T Helper Cell Apoptosis Is the Basic Mechanism of Ultraviolet-A Radiation Phototherapy

  The Journal of Experimental Medicine · 1997 · 10.1084/jem.186.10.1763

• A Short-Term Trial of Tacrolimus Ointment for Atopic Dermatitis

  New England Journal of Medicine · 1997 · https://doi.org/10.1056/nejm199709183371203

• Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system.

  PubMed · 1997

Current projects

No projects listed.