Dirk Reinhardt

Research interests

Publications

• The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets

  Cancer Discovery · 2021 · https://doi.org/10.1158/2159-8290.cd-21-0094

• The genetic basis and cell of origin of mixed phenotype acute leukaemia

  Nature · 2018 · https://doi.org/10.1038/s41586-018-0436-0

• Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012

  Leukemia · 2018 · https://doi.org/10.1038/s41375-018-0071-7

• Pediatric non–Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes

  Nature Genetics · 2017 · https://doi.org/10.1038/ng.3772

• Childhood cancer predisposition syndromes—A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology

  American Journal of Medical Genetics Part A · 2017 · https://doi.org/10.1002/ajmg.a.38142

• Next-generation personalised medicine for high-risk paediatric cancer patients – The INFORM pilot study

  European Journal of Cancer · 2016 · https://doi.org/10.1016/j.ejca.2016.06.009

• Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia

  Journal of Clinical Oncology · 2015 · https://doi.org/10.1200/jco.2015.62.8289

• Improved Outcome in Pediatric Relapsed Acute Myeloid Leukemia: Results of a Randomized Trial on Liposomal Daunorubicin by the International BFM Study Group

  Journal of Clinical Oncology · 2013 · https://doi.org/10.1200/jco.2012.43.7384

• Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel

  Blood · 2012 · https://doi.org/10.1182/blood-2012-03-362608

• NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern

  Blood · 2011 · https://doi.org/10.1182/blood-2011-04-346643

• miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia

  Genes & Development · 2010 · https://doi.org/10.1101/gad.1856210

• Prognostic Impact of Specific Chromosomal Aberrations in a Large Group of Pediatric Patients With Acute Myeloid Leukemia Treated Uniformly According to Trial AML-BFM 98

  Journal of Clinical Oncology · 2010 · https://doi.org/10.1200/jco.2009.25.6321

• Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study

  Blood · 2009 · https://doi.org/10.1182/blood-2009-04-215152

• Cardiac Involvement in Churg-Strauss Syndrome

  Medicine · 2009 · https://doi.org/10.1097/md.0b013e3181af35a5

• Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestration

  Leukemia · 2008 · https://doi.org/10.1038/leu.2008.103

• Treatment and prognostic impact of transient leukemia in neonates with Down syndrome

  Blood · 2008 · https://doi.org/10.1182/blood-2007-10-118810

• Clinical implications of FLT3 mutations in pediatric AML

  Blood · 2006 · https://doi.org/10.1182/blood-2006-03-009233

• Respiratory health and individual estimated exposure to traffic-related air pollutants in a cohort of young children

  Occupational and Environmental Medicine · 2006 · https://doi.org/10.1136/oem.2006.028241

• Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia

  Leukemia · 2005 · https://doi.org/10.1038/sj.leu.2403870

• Treatment strategies and long-term results in paediatric patients treated in four consecutive AML-BFM trials

  Leukemia · 2005 · https://doi.org/10.1038/sj.leu.2403920

• AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity

  Leukemia · 2005 · https://doi.org/10.1038/sj.leu.2403814

• Early Deaths and Treatment-Related Mortality in Children Undergoing Therapy for Acute Myeloid Leukemia: Analysis of the Multicenter Clinical Trials AML-BFM 93 and AML-BFM 98

  Journal of Clinical Oncology · 2004 · https://doi.org/10.1200/jco.2004.01.191

• Infectious complications in pediatric acute myeloid leukemia: analysis of the prospective multi-institutional clinical trial AML-BFM 93

  Leukemia · 2003 · https://doi.org/10.1038/sj.leu.2403188

• Traffic-related air pollution and respiratory health during the first 2 yrs of life

  European Respiratory Journal · 2002 · https://doi.org/10.1183/09031936.02.01182001

• Improved Treatment Results in High-Risk Pediatric Acute Myeloid Leukemia Patients After Intensification With High-Dose Cytarabine and Mitoxantrone: Results of Study Acute Myeloid Leukemia–Berlin-Frankfurt-Münster 93

  Journal of Clinical Oncology · 2001 · https://doi.org/10.1200/jco.2001.19.10.2705

Current projects

No projects listed.